[3 special bronchial cases].
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Biomedical subjects
Publications and source records attributed to G Melillo.
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UNLABELLED: Several methods of bronchial challenging have been described in literature. The comparison of the results obtained in different departments is, of course, very difficult. The Authors have been interested in the standardization of inhalation challenge techniques and they present in this work their method and the results obtained. The standardized method has a good specificity, because of the agreement between B.P.T. and other diagnostic tests. The bronchial reaction generally developes after the exposition to low doses of allergen extract, and this confirms the specificity of the method. Its precision, depending on the standardization of allergen extract activity by RAST and of inhalation procedures, is good. The reproducibility is of 100 per cent. The safety is high (rare untword reactions). IN CONCLUSION: this standardized method of bronchial challenging is useful in etiologic diagnosis of asthma.
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In this report we have described the statistical results of a clinical study on 2362 asthmatic patients living mostly in the Naples area and observed in our Division of Respiratory Allergy from January 1976 to May 1978. All data have been analyzed by a computerized method using an Univac 1100 Computer. We have studied some aspects of the atopic syndrome in this population of Southern Italy: frequency of allergic sensitization according to endogenous and extrinsic factors (particularly Parietaria officinalis, a characteristic pollen of the Southern Italian Flora), etc. Finally we have presented the first results of our allergological investigation in Naples concerning the distribution of allergic sensitization according to air pollution of the patient's home.
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