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Biomedical subjects

G Medina-Escobedo

Publications and source records attributed to G Medina-Escobedo.

5 recordsLinked to original sources

Sling left pulmonary artery, bridging bronchus, and associated anomalies.

Sling left pulmonary artery (SLPA) is often associated with tracheobronchial abnormalities, including bridging bronchus (BB). We report on 3 patients with SLPA: One patient had a narrow trachea, absent right upper lobe and right main bronchus, and BB. The second patient had a long and narrow trachea, with normal segmentation of bronchial tree, abnormal cerebral gyri, and minor facial abnormalities. The third patient, with a normal trachea and main bronchi with BB, had imperforate anus, hemivertebrae, and atrial septal defect (VATER association). Patients with SLPA, those with BB, or those with both SLPA and BB as well as multiple congenital anomalies represent a spectrum of anomalies.

Abnormalities, Multiple↗

Bulky naevocytoma of the perineum: a singular variant of congenital giant pigmented naevus.

We describe two instances of a previously unrecognized variant of congenital giant pigmented naevus (GPN), presenting as a bulky naevocytic tumour in the perineal region. In both cases the lesion was present at birth and attained massive dimensions. In addition to the characteristic histological patterns found in GPN, which included extensive areas with a neural appearance, these tumours presented an uncommon tendency to form pseudo-follicular structures lined by naevus cells. No features suggestive of malignant transformation were found. Because GPN may associate with an underlying malignancy, accurate diagnosis of this lesion is important in clinical practice.

Humans↗

[The VATER association].

The clinical, radiologic, and anatomic features of 53 patients with VATER association were reviewed. The vertebral, anorrectal, tracheoesophageal, radial, and renal congenital defects included in the association are similar to those described by other authors. In this report genital anomalies are very frequent and should be included as a diagnostic criteria for this association. Encephalic, facial, and cranial congenital defects are common and can affect prognosis; 17 patients have other malformations patterns, and they can belong to a different group of malformations.

Abnormalities, Multiple↗

Ectopia cordis: autopsy findings in four cases.

Ectopia cordis (EC) is a rare congenital malformation characterized by the abnormal position of the heart outside the thorax. Since it is often associated with intracardiac anomalies, an adequate surgical approach requires a precise knowledge of the intra- and extracardiac morbid anatomy. We report 4 cases of EC with a detailed description of intracardiac findings at autopsy. The associated malformations were severe and aggravated the outcome. Intracardiac anomalies are sometimes mild, but can be associated with a severe extracardiac defect.

Abdomen↗