Search PubMed⌕ Search

Biomedical subjects

G McBride

Publications and source records attributed to G McBride.

48 records · Page 3Linked to original sources

The isolation syndrome in childhood.

A new diagnostic category--the Isolation Syndrome--is proposed to describe a pattern of abnormal behaviour in children. The child's 'isolated' state manifests itself in defective social interaction and communication between mother and child, in disorders of perceptual function and motor skills, in stereotyped behaviour and in general developmental retardation, especially in language. The typical situations in which the syndrome is likely to occur are discussed, and methods of treatment, both prophylactic and remedial, are given in detail. The purpose of identifying the Isolation Syndrome is to alert clinicians to the possibility that in some children with abnormal patterns of behaviour there is a specific and treatable difficulty in the child's environment.

Affective Symptoms↗

Hypothyroidism due to destruction of the thyroid by Kaposi's sarcoma.

A case of hypothyroidism that manifested as depression and deteriorating functional status and that ultimately resulted in the death of a 41-year-old patient with AIDS is described. Postmortem examination revealed destruction of the thyroid gland by Kaposi's sarcoma. Analysis of stored serum samples revealed that the patient had become profoundly hypothyroid during his terminal illness. Practitioners are reminded of the need to exclude metabolic causes when treating encephalopathy in patients infected with human immunodeficiency virus.

Acquired Immunodeficiency Syndrome↗