Search PubMed⌕ Search

Biomedical subjects

G Masini

Publications and source records attributed to G Masini.

At least 37 records · Page 2Linked to original sources
PubMed1979

The antibody response in chronic pyelonephritis.

Serum antibodies specific for the bacteria isolated from the urines of 41 patients with chronic pyelonephritis and 14 with asymptomatic bacteriuria were assayed. Even though it is clear that infections which involve the kidney evoke higher antibody responses than do purely bladder infections, it is difficult to establish a cut-off level for distinguishing the two by this method. There is a greater probability that there will be an upper urinary tract infection without an antibody response than that there will be a good antibody response in cases with lower tract infections. In our case list, 49% of the patients with chronic pyelonephritis had titers equal to or greater than 1:400, and another 44% had titers between 1:50 and 1:100. Therefore it appears that the magnitude of the antibody response depends not only on the location of the infection but also on other factors, such as the intrinsic immunogenicity of the different bacterial strains and the properties of the immunological system of the patient.

Adolescent↗
PubMed1978

[Cardiac pacing in sinus node disease (author's transl)].

In sinus node disease, cardiac pacing is used as a diagnostic and therapeutic tool. The assessment of sinus node recovery time by means of rapid atrial pacing and sino-atrial conduction time by means of premature atrial stimulation, are the methods usually utilized in the diagnosis of sino-atrial dysfunctions. Theoretical and practical limitations however induce to careful evaluation of the results. Heart pacing is also useful for the treatment of sino-atrial dysfunctions. However, criteria for pacemaker implantation in these conditions are still lacking and the type of pacemaker indicated is not defined yet. At present, the accurate clinical investigation of the patient still remains the best guide to therapeutical approach.

Cardiac Pacing, Artificial↗
PubMed1977

Analysis of the interpolation phenomenon in man evaluated by premature atrial stimulation.

After early premature atrial stimulations, returning cycles shorter than the basic cycle were observed in 25 patients. In 4 of them sinus echoes were seen to occur after premature atrial stimulation coupling intervals shorter than those able to induce completely interpolated beats. Such a sequence is unexpected if we suggest a sino-atrial entrance block for explaining the interpolation phenomenon. An alternative explanation can be postulated assuming that all these early premature beats are sinus node re-entries and that the completely interpolated beat is only a sinus re-entry fortuitously occurring at an appropriate interval.

Adult↗
PubMed1975

Analysis of sino-atrial conduction in man using premature atrial stimulation.

Sino-atrial conduction was investigated using premature atrial depolarization in 25 patients seven of whom had sino-atrial block. The results obtained in this investigation were evaluated plotting the test cycle (expressed as difference between the basic sinus cycle and the test cycle as a percentage of the basic sinus cycle) as a function of the return cycle (expressed as difference between the return cycle and the basic cycle as a percentage of the basic sinus cycle). In normal subjects, premature atrial depolarizations elicited in the last 10-20% of the spontaneous sinus cycle, produced a progressive prolongation of the return cycle and the points correlating the return cycle index to the test cycle index fell above the diagonal of the plotting system. After earlier premature atrial depolarizations, the return cycle remained of the same length, and the points correlating the return cycle index to the test cycle index fell along a line parallel to the y-axis ('plateau'). The mean value of the returning cycles (as expressed above) corresponding to the test cycles (as evaluated above) included in the first 5% of the 'plateau' can be defined as 'the sino-atrial conduction index'. This index, the sum of conduction into and out of the sinus node, was found to range from 79 to 185 ms. By assuming similar anterograde and retrograde conduction, the sino-atrial conduction time ranged from 39.5 to 97.5 ms (mean value=70 ms). In the patients with sino-atrial block, fully compensatory pauses were observed for atrial premature depolarizations elicited up to the last 25-35% of the atrial cycle, and a slow and progressive divergence from the diagonal of the plotting system was seen instead of the 'plateau'. In these patients the sino-atrial conduction index ranged from 151 to 297 ms (mean 253 ms). By assuming similar antegrade and retrograde conduction, the sino-atrial conduction time ranged from 75.5 to 148.5 ms (mean value=126.5 ms) with a statistically significant difference with respect to normal subjects (P=0.001).

Adult↗
PubMed1975

[Programmed atrial stimulation in the study of sinoatrial conduction in normal subjects (author's transl)].

Sinoatrial conduction was investigated in 18 normal subjects, using premature atrial depolarizations. The results obtained in this investigation were evaluated plotting the test cycle (expressed as difference between the basic sinus cycle and the test cycle as a percentage of the basic sinus cycle) as a function of the return cycle (expressed as difference between the return cycle and the basic cycle as a percentage of the basic sinus cycle). In normal subjects, premature atrial depolarizations elicited in the last 10-20% of the spontaneous sinus cycle, produced a progressive prolongation of the return cycle and the points correlating the return cycle index to the test cycle index fell above the diagonal of the plotting system. After earlier premature atrial stimulations, the return cycle stayed the same length, and the points correlating the return cycle index to the test cycle index fell along a line parallel to "y" axis (plateau). The mean value of the returning cycle (expressed as above) corresponding to the test cycles (evaluated as above) included in the first 5% of the "plateau" can be defined as the "sinoatrial conduction index". This index, the sum of conduction into and out of the sinus node, ranged from 79 msec to 187 msec. By assuming similar anterograde and retrograde conduction, the sinoatrial conduction time ranged from 39.5 msec to 97.5 msec (mean value 70 msec).

Adult↗
PubMed1975

[Functional block in the His-Purkinje system (author's transl)].

In nine patients without clinical or laboratory evidence of heart disease, premature atrial depolarization (PAB) induced a complete block of conduction in the intraventricular conducting system. In these patients the functional refractory period AV (FRPav)) gave short and very similar results to the effective refractory period of the His-Purkinje system (ERPhp), and the effective refractory period AV (ERPAV) was found to be shorter than the ERPhp in all cases. A linear correlation between the ERPhp and the basic cycle length (BCL) was also observed. These special functional properties of the AV node justify the occurrence of intraventricular block after PAB. In fact, the stimulus, rapidly conducted through the AV node, finds a complete or incomplete refractoriness in the ventricular conducting system, and therefore bundle branch or complete intraventricular block occurs. The linear correlation between the ERPHP and the BCL explains why the atrial pacing is not always useful for pointing out intraventricular conducting defects.

Adult↗