[Paretic sequels of acute anterior poliomyelitis. Repercussions on personality development and intellectual development].
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Biomedical subjects
Publications and source records attributed to G Maria.
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Two methods of treating the perineal wound after proctectomy are compared. One hundred and eleven patients had a Miles operation for rectal cancer: in 81 the perineal wound was left open, in 30, primary suture and suction were performed. A significant (p less than 0.001) decrease in the mean (+/- s.d.) duration of the postoperative period was observed after primary suture: 22 +/- 1.7 days, as compared with 44 +/- 2.2 days after healing by second intention. The occurrence of wound infection was similar in the two groups, whereas in 15 per cent of the patients treated without direct closure, a perineal sinus persisted. According to these data, primary closure seems to be very satisfactory in the management of the perineal wound after excision of the rectum.
The Authors were interested in the palmo-mental reflex, pointing out the frequency of it in patients with neurological diseases and not, and suggested a hypothesis on the neurophysiological mechanism to the basis of its clinical manifestation.
The Authors care about the Isaacs disease; they describe a clinical case and report the result trough carbamazepine and diphenylhydantoin. They think that the hypothesis of nerve suffering, of motor plate suffering does not explain the clinical syndrome. The Authors hypothesize a functional change in the trophic proteins and in the balance excitation-inhibition and neuromodulation. This would explain therefore both the motor syndrome and the vegetative syndrome.
The authors report a case of cystic neoplasm of the pancreas treated by cystojejunostomy two years and half earlier. On that occasion, a false diagnosis of pancreatic pseudocyst had been suggested. Cystic neoplasm of the pancreas has a far better prognosis than adenocarcinoma. However, early detection is difficult and erroneous initial diagnosis may lead to delayed treatment and poor long-term results. In our case, though surgical treatment was aggressive and apparently radical, early recurrence of neoplasm was observed. Only early accurate diagnosis of pancreatic cystadenocarcinoma might improve the results of surgical treatment.
BACKGROUND/AIMS: The authors compared the results of the Nissen fundoplication technique with the results of the Hill procedure, by using a 10-year history of patients with gastro-esophageal reflux disease. MATERIALS AND METHODS: Seventy two consecutive patients entered the study, 32 of whom underwent a 360 degrees fundoplication according to Nissen and 40 with a modified Hill operation. In the Nissen Group, intraoperative manometry (IOM) was carried out in all patients; in the Hill Group, the patients were randomized in two sub-groups (A and B), before operation; in 20 of them (group A), the procedure was randomly associated to IOM. RESULTS: The overall complications were low in both groups (15.6% in the Nissen Group and 5% in the Hill Group, p = 0.1), and there was no mortality rate. The clinical results were excellent or good in 28 patients (87.6%) of the Nissen Group and in 36 patients (90%) of the Hill Group (p = 0.5); in particular, an excellent outcome was observed in 16 patients (80%) with IOM (sub-group A), while 12 patients (60%) without it (sub-group B) showed similar results. The manometric studies carried out six months after surgical treatment showed a decrease of the lower esophageal sphincter pressures in all patients if compared to the pressure recorded intra-operatively. In comparison to the pre-operative values, both the lower esophageal sphincter length and its intra-abdominal portion were markedly increased in the Nissen Group and in the sub-group A of the Hill patients. CONCLUSIONS: These results support the conclusions that modified posterior gastropexy and 360 degrees fundoplication are effective, well tolerated, and can be properly used in the treatment of Gastro-esophageal reflux disease (GERD), since both techniques showed good clinical results. A favorable clinical outcome depends mostly on adequate lower esophageal sphincter length (LESL) and LESIA extension, which could be more efficiently achieved by the use of intraoperative manometry (IOM).