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Biomedical subjects

G Mann

Publications and source records attributed to G Mann.

At least 127 records · Page 7Linked to original sources

A disorder of rapid eye movement sleep in a cat.

A young female cat with no neurologic abnormality during wakefulness was discovered to have violent motor activity during rapid eye movement sleep. Various characteristics of the disorder, which differentiated these episodes from epileptic seizures, suggested that the movements resulted from an exaggeration of phasic excitation during rapid eye movement sleep.

Animals↗

Envenoming by Cerastes viper - a report of two cases.

Two cases of envenoming by Cerastes vipera are described Both were in snake collectors who were accidentally bitten on the finger while handling the snake. In both cases, local signs included a haemorrhagic bulla with fang marks, swelling and tenderness. These signs were mild in one case and moderately severe in the other, necessitating fasciotomy. No systemic signs were observed. Some coagulation abnormalities were found in both cases. In one, prolonged bleeding from the wound and a shortened euglobulin lysis time may suggest activation of the fibrinolytic mechanism. In the other, prolongation of prothrombin time occurred with no haemorrhagic diathesis. Treatment included fasciotomy in one case and elevation of the affected part and antibiotics in the other. It appears that the clinical course of this snakebite is relatively benign.

Adolescent↗

[Not Available].

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Historiography↗

Evaluation of plaque size reduction as a method for the detection of Pichinde virus antibody.

The reaction between Pichinde virus and homologous antisera has been studied using a plaque size reduction method. The incorporation of antiserum in the overlay of infected Vero cell monolayers revealed a pattern of virus-cell interactions which were manifested by both a significant reduction in the diameter of virus plaques, and regeneration of cells in the centre of each. Electron microscopy demonstrated that antibody molecules were bound to virus particles budding from the surface of infected cells resulting in the formation of extracellular virus-antibody complexes. These aggregates were subsequently detected in vacuoles of freshly-infected cells. In the absence of virus neutralization, reaction of Pichinde virus with homologous antiserum leads to the formation of infectious aggregates which due to their larger size restrict the rate of plaque development.

Animals↗

[Not Available].

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Germany↗

Adhesion of enteropathogenic bacteria to cells in tissue culture.

Adhesion to the intestinal mucosa is the primary determinant of virulence among bacteria causing intestinal disease. Most current test systems involve the use of animal or foetal tissue. This paper illustrates the ability of enteropathogenic bacteria to adhere to mammalian cells. The test described enables considerable differences in adherence to be demonstrated between bacterial strains.

Animals↗

[Not Available].

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Biological Evolution↗

Echis colorata bites in Israel: an evaluation of specific antiserum use on the base of 21 cases of snake bite.

Specific Antiserum for Echis colorata snake bite has been in use since 1965. To date 25 cases of bite by this snake have been reported, most of which are included in this series. As the antiserum was not routinely used I had the opportunity to compare the results in patients receiving antiserum to the results in patients not receiving it. The conclusion is that the use of specific antiserum should be limited to patients demonstrating severe bleeding and not reacting to treatment of consumption coagulopathy. The clinical picture, laboratory results and the post mortem results of a fatal case of E. colorata bite are included.

Adolescent↗