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Biomedical subjects

G Mandelli

Publications and source records attributed to G Mandelli.

25 records · Page 2Linked to original sources

[Occupational disease in construction work].

BACKGROUND: There are very few studies in the Italian and international literature concerning occupational diseases and their prevention in the building industry. OBJECTIVES: The aim of this study was risk assessment in the building industry. METHODS: We analyzed the international literature and the results of our cross-sectional study, which involved more than 1000 workers. RESULTS: The analysis of several studies and of our experience suggests a high occupational risk in this field and shows as main risk factors: noise, dusts, fibers, manual lifting, prolonged static positions, repetitive motions, hand-shoulder and whole-body vibrations, chemicals and weather conditions. In addition, non-occupational risk factors can influence health: e.g., habits and lifestyle, like hypercaloric diet, cigarette smoking and alcohol consumption. CONCLUSIONS: Preventive measures and training initiatives are urgently needed to improve the safety and the health among building workers.

Adult↗

[Introductional results of a mortality study in 471 ex-exposed workers to PCBs].

This study concerned a group of ex-workers (372 males and 99 females) from a firm situated in Bergamo (Italy) that ceased its activity at the beginning of the Nineties. From an introductory analysis of the results, we found out that there isn't excess in the death-rate for liver and bile ducts cancers among the males of this group. Among them, for what concerns the other tumoral pathologies, such as leukaemia and stomach tumors, the information allowed to verify an excess of mortality. However, this increase hasn't result statistically significant. On the contrary, it came out that there is an excess of risk for intestine tumors: standardized death-rate of 2.58. In accordance with the information collected, for the future it will be necessary to carefully examine the research in order to verify the existence of a direct connection to the exposure at PCB and study the incidence (not only for mortality) of these neoplasms.

Bile Duct Neoplasms↗

The gross and histological findings in the liver of pigs with Aujeszky's disease.

The gross and histological changes were studied in the liver of young pigs naturally infected with Aujeszky's disease. In the majority of the cases examined it was possible to detect small necrotic foci, scattered throughout the liver parenchyma, which corresponded histologically with intralobular or plurilobular areas of coagulative necrosis. At the periphery of the larger necrotic foci, inclusion bodies were also found in the hepatocytes of 9 of the 17 pigs examined. These intranuclear inclusion bodies showed various developmental features, similar to those reported quite frequently in herpesvirus infections of animals.

Animals↗