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Biomedical subjects

G Maisano

Publications and source records attributed to G Maisano.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Theoretical bases of health education in cardiology: the secondary prevention of ischemic heart disease].

The secondary prevention of ischemic heart disease must, at the right time, recognize and efficaciously treat the categories of the illness (myocardial infarction, angina pectoris, heart failure, arrhythmias, sudden death) and restrain its development. The success of such a preventive program involves the active cooperation of the patient who, for this reason, has to be motivated by suitable information. So a proper cardiac information technique is indispensable; it has to involve: the patient, his family, his physician and, more generally, politicians, medical workers, employers. The Authors explain the education and counseling program, started 15 years ago, in accordance with the following scheme: users, goals, educational and counseling methods.

Coronary Disease↗
PubMed1981

[Prajmalium bitartrate in hyperkinetic ventricular arrhythmias in infarct patients during rehabilitation].

The present study was designed to assess the antiarrhythmic Prajmalium Bitartrate (PB) efficacy in the long term treatment of 22 patients with recent myocardial infarction and persistent, frequent, polimorphous, repetitive (two or more in a row) ventricular premature complexes (VPCs). VPCs were exposed by means of 24-hours ambulatory monitoring. The acute drug testing with a single dose of PB (30 mg) was followed by multiple maintenance therapy with a dose decreasing from 60 to 40 mg every day. Than, the long term antiarrhythmic action was evaluated by both monitoring and exercise stress testing (EST), symptom self-limited, in a 7 months and 28 days follow-up. A favorable therapeutic effect, with a reduction of VPCs frequency greater than 85% and the suppression of their greater Lown degrees, was obtained in 13 cases (59.2%) using PB alone and in 6 cases (27.2%) using PB associated with Amiodarone in 5 patients and with Metoprololo in one. No VPCs were present or they were less than 2 every 3 minutes during EST. Fourteen patients reported a recurrence of VPCs when the drug was stopped for 24-28 hours, after 3-5 months of the treatment. In 3 patients (13.6%) the PB was uneffective. In a case there was, during the acute drug testing, a paradox increasing of the arrhythmias, and in the other two an abnormal lengthening of QTc interval, while arrhythmia was unchanged. PB, alone or associated with other antiarrhythmic drugs, appears a well tolerated, handy and effective agent and it can be proposed as a drug of first choice for controlling VPCs.

Adult↗