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Biomedical subjects

G Mage

Publications and source records attributed to G Mage.

At least 127 records · Page 7Linked to original sources

Laparoscopic management of adnexal torsion. A review of 35 cases.

Laparoscopic management was used for 35 cases of adnexal torsion. Since early diagnosis and treatment are necessary to preserve the adnexa, laparoscopy is the best procedure for diagnosing this rare condition. In 27 cases (77%) conservative treatment was carried out, with only 1 recurrence. Complete laparoscopic treatment was achieved in 27 cases (77%), including 3 of endoscopic salpingectomy. Laparotomy was indicated in cases of gangrenous adnexa, organic ovarian cyst and unusual ovarian attachment.

Adnexal Diseases↗

Laparoscopic treatment of endometriosis.

Adequate management of endometriosis by laparoscopy included 3 steps: a laparoscopic diagnosis with peritoneal fluid sampling for cytologic examination and biopsies of implants and of peritoneum to assure a correct diagnosis, a laparoscopic evaluation of extension with the American Fertility Society (AFS) 85 scoring system in order to classify the severity of the disease, and a laparoscopic treatment with the following strategy: drainage of the ovarian endometrioma and careful peritoneal washing, treatment of peritoneal implants, ovariolysis, treatment of the ovarian cysts, hemostasis and peritoneal lavage. Treatment of peritoneal implants is very easily performed by CO2 laser vaporization using a suprapubic puncture. Ovarian endometriomas are treated by laparoscopic cystectomy using a transparietal cystectomy or an intraperitoneal cystectomy. Laser vaporization is used only in case of small ovarian cysts or after an incomplete resection of a large cyst. Results of laparoscopic treatment of endometriosis compare favorably with those obtained with surgical procedures performed by laparotomy with the well known advantage of a laparoscopic approach.

Adult↗

[Decrease of HCG level after conservative laparoscopic treatment of extra-uterine pregnancy].

HCG levels have been studied in 76 patients following laparoscopic treatment using laparotomy. This shows that early detection of treatment failure is possible of ectopic pregnancy. The decrease of HCG was the same as after conservative treatment from the third or fifth post-operative day onwards. The authors report a scheme for the post-operative follow-up after laparoscopic treatment of ectopic pregnancy based on the rate of HCG decrease.

Chorionic Gonadotropin↗

CO2 laser microsurgery: five years experience with long-term results.

Techniques and results of CO2 laser microsurgery are reported from a series of 123 patients operated on between 1979 and 1983. Salpingostomy was carried out in 76 patients, reversal of sterilization in 16 patients, reanastomosis for pathologic disease in 12 patients, and combined procedures in 19 patients. Results compare favorably with conventional microsurgery. CO2 laser surgery appears to be a very effective technique and is very easy to achieve in microsurgery. Correct use of CO2 laser is required in order to obtain a good post-operative success rate. The surgeon must be competent in microsurgery and in laser technology.

Adult↗

[Decrease in HCG levels after conservative laparoscopic treatment of extra-uterine pregnancy].

Dropping hCG levels have been studied in 76 patients following laparoscopic treatment of ectopic pregnancy. The drop in hCG is the same as after conservative treatment using laparotomy. This study shows that early detection of treatment failure is possible from the third or fourth post-operative day onwards. The authors report a scheme for the post-operative follow-up after laparoscopic treatment for ectopic pregnancy relying on the hCG rate.

Chorionic Gonadotropin↗

[Ovarian cysts and celioscopy. Apropos 226 cases].

Tumours of the adnexae are frequent. In most cases it is necessary to look at them directly and to treat them surgically. Laparatomy is a heavy technique. For this reason we use the laparoscope to diagnose cystic lesions and to treat benign tumours. This retrospective study on 226 patients has given us the opportunity to assess the value of the laparoscope in these conditions. From the diagnostic point of view laparoscopy is reliable. No malignant tumour failed to be diagnosed (100% reliable), the anatomopathological examination of specimens in benign conditions was never wrong (100% reliable). Laparoscopy therefore is a reliable way of diagnosing the type of ovarian cyst. 180 patients were treated using the laparoscope (79.5%). The patients were followed up for 1 to 5 years. We have not had a recurrence of a cyst treated in this way. Each time a malignant tumour was diagnosed or even suspected the classical surgical approach by laparotomy was always carried out. For a trained surgeon laparoscopy seems to be a reliable method of diagnosing and treating. It possesses the very well-known advantages of minimal operative trauma and far less cost.

Adolescent↗

A preoperative classification to predict the intrauterine and ectopic pregnancy rates after distal tubal microsurgery.

A simple preoperative classification is described to predict the intrauterine and ectopic pregnancy rates following distal tubal microsurgery. Laser CO2 microsurgical salpingostomies were performed on 76 patients between January 1979 and January 1984. All of the patients underwent a preoperative assessment, which included hysterosalpingogram and laparoscopy, to formulate a preoperative classification based on a point system. The patients were divided into four groups according to tubal damage, with a subsequent intrauterine pregnancy rate of 58.3% in grade I, 36.6% in grade II, 9.5% in grade III, and 0% in grade IV. The patients were divided into four groups according to adhesions, with a subsequent intrauterine pregnancy rate of 38.8% with no adhesion, 32.0% with mild adhesions, 26.6% with moderate adhesions, and 5.5% with severe adhesions. From these results, a preoperative management is proposed for patients being considered for either distal tubal microsurgery or in vitro fertilization.

Adult↗

Conservative laparoscopic treatment of 321 ectopic pregnancies.

From 1974 to 1984, 321 tubal pregnancies were treated conservatively with laparoscopic techniques. Fifteen cases (4.8%) required a subsequent laparotomy or second laparoscopic procedure because of retained trophoblastic tissue. Of 118 patients desiring subsequent pregnancy, 76 had an intrauterine pregnancy (64.4%) and 26 had a second ectopic pregnancy (22%). Eleven of 24 (45.8%) women attempting conception following conservative laparoscopic removal of an ectopic gestation from the sole remaining fallopian tube established an intrauterine pregnancy. In this same group, seven patients (29.2%) had a second ectopic pregnancy. The fertility results were also analyzed according to the previous history. The postoperative intrauterine pregnancy rate was 85.5% among 62 patients without a history of infertility (group I), compared with 41.1% among 56 patients with a history of infertility or a previous ectopic pregnancy (group II). The subsequent ectopic pregnancy rate in group I was 16.1% versus 28.6% in group II. This large series clearly demonstrates the relative safety and efficacy of conservative laparoscopic treatment of tubal pregnancies.

Adolescent↗

Treatment of acute salpingitis with sulbactam/ampicillin. Comparison with cefoxitin.

Sulbactam/ampicillin and cefoxitin were compared in the treatment of 20 patients with acute salpingitis diagnosed during laparoscopy. Results were evaluated during laparoscopic follow-up at 2 months. Sulbactam/ampicillin appeared to be a better treatment, producing better results in tubal patency, adhesions and persistent inflammation than cefoxitin. In addition, the combination of sulbactam/ampicillin with doxycycline appears to provide better results than the combination of cefoxitin with doxycycline in chlamydial salpingitis. It is concluded that sulbactam/ampicillin is an effective treatment for nonchlamydial salpingitis.

Acute Disease↗

[Celioscopic treatment of extra-uterine pregnancy].

The treatment of extrauterine pregnancy by coelioscopy is the most extreme refinement of coelioscopic surgery. It is recorded in the modern context of endoscopic surgery. This technique was received with reserve some years ago, when we presented the first case. After more than 250 cases the validity of the treatment has been established, and it has been adopted by other groups, foreigners in particular. It is applicable to non-ruptured tubal pregnancies, and necessitates an early diagnosis. Compared with techniques carried out by laparotomy, it offers the advantage of considerable gain of operative time, and of a considerable reduction in hospitalization, with excellent results on later fertility.

Endoscopy↗

[Celioscopy in the early follow-up of salpingitis].

The authors report their findings in 34 cases of salpingitis that were diagnosed and controlled laparoscopically one month after treatment had been finished. Four different elements came up: persistence of inflammation, adhesions, tubal patency and the prognosis for future fertility. It would seem that these last three criteria depend greatly on the seriousness at first of the salpingitis, as opposed to the degree of persistent inflammation. The authors show how valuable laparoscopic drainage of a pyosalpinx is and how valuable laparoscopic control after salpingitis is. Having been given these features they can visualise a new approach to the diagnosis and treatment of pelvic infection.

Adolescent↗

[In vitro study of fibroblasts from patients with Duchenne muscular dystrophy. Evaluation of capping and ultrastructural aspect].

There have been conflicting studies of lymphocyte capping from patients with Duchenne Muscular Dystrophy. We have evaluated the proportion of capped fibroblasts of 10 patients with Duchenne Muscular Dystrophy. The results, compared with 15 normal controls, showed that the reduction of fibroblast capping is correlated to age patients. Additional studies, decreased number of retracted fibroblasts after colchicine incubation and ultrastructural observations, suggest that capping deficit would be the consequence of microtubular system alteration. This late phenomenon may be secondary to the primary membrane defect.

Adolescent↗