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Biomedical subjects

G M Lyons

Publications and source records attributed to G M Lyons.

21 records · Page 2Linked to original sources

Data logging technology in ambulatory medical instrumentation.

This paper reviews the advancements made in ambulatory data logging used in the study of human subjects since the inception of the analogue tape based data logger in the 1960s. Research into the area of ambulatory monitoring has been rejuvenated due to the development of novel storage technologies during the 1990s. Data logging systems that were previously impractical due to lack of processing power, practical size and cost are now available to the practitioner. An overview of the requirements of present day ambulatory data logging is presented and analogue tape, solid-state memory and disk drive storage recording systems that have been described in the literature are investigated in detail. It is proposed that digital based technology offers the best solution to the problems encountered during human based data logging. The appearance of novel digital storage media will continue the trend of increased recording durations, signal resolution and number of parameters thus allowing the momentum gained throughout the last several decades to continue.

Humans↗

Finite state control of functional electrical stimulation for the rehabilitation of gait.

Finite state control is an established technique for the implementation of intention detection and activity co-ordination levels of hierarchical control in neural prostheses, and has been used for these purposes over the last thirty years. The first finite state controllers (FSC) in the functional electrical stimulation of gait were manually crafted systems, based on observations of the events occurring during the gait cycle. Subsequent systems used machine learning to automatically learn finite state control behaviour directly from human experts. Recently, fuzzy control has been utilised as an extension of finite state control, resulting in improved state detection over standard finite state control systems in some instances. Clinical experience over the last thirty years has been positive, and has shown finite state control to be an effective and intuitive method for the control of functional electrical stimulation (FES) in neural prostheses. However, while finite state controlled neural prostheses are of interest in the research community, they are not widely used outside of this setting. This is largely due to the cumbersome nature of many neural prostheses which utilise externally mounted gait sensors and FES electrodes. FES-based control of movement has been subject to the constraints of artificial sensor and FES actuator technologies. However, continued advances in natural sensors and implanted multi-channel stimulators are broadening the boundaries of artificial control of movement, driving an evolutionary process towards increasingly human-like control of FES-based gait rehabilitation systems.

Electric Stimulation Therapy↗

Decelerative changes in heart rate are associated with performance on tasks that assess intelligence.

Changes in heart rate, chin electromyographic (EMG) activity, and respiration rate were monitored during the performance of three tasks that are commonly employed to assess intelligence in human adults. Stimuli from the digit span subtest (Expt. 1) of the Wechsler scales of intelligence, the picture completion subtest (Expt. 2), and the picture arrangement subtest (Expt. 3) were employed. A 10-s warning preceding the onset of each stimulus was also used in each of the experiments. During all three tasks there was an initial increase in heart rate during the first 3-4 s of the warning signal, followed by a decrease in heart rate during the last 5-6 s of the warning signal. Mean heart rate during the 5 s immediately preceding the presentation of stimuli to which subjects gave correct responses was significantly lower than mean heart rate during the 5 s immediately preceding the presentation of stimuli to which subjects gave incorrect responses. In addition, mean heart rate during the 5 s immediately preceding the presentation of stimuli to which subjects gave correct responses decreased significantly below the pre-warning baseline level, whereas mean heart rate during the 5 s preceding the presentation of stimuli to which subjects gave incorrect responses did not decrease below the baseline level. The differential heart rate results for correct and incorrect responses were consistent across the three tasks. No significant changes in chin EMG and respiration rate were noted during any of the tasks. Relationships among heart rate, attention to environmental information, and the role of attention in measures of intelligence are discussed.

Adolescent↗