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Biomedical subjects

G M Koppes

Publications and source records attributed to G M Koppes.

13 recordsLinked to original sources
PubMed1980

Complication rate of power coronary angiography injection.

From 1970 to 1975, 1,498 patients underwent coronary angiography at Wilford Hall USAF Medical Center via the same injection technique utilizing a Viamonte Hobbs automatic volume injector. Most institutions now perform coronary angiography by hand injections of contrast medium, and automatic power injection angiography is reserved for ventriculograms. The Sones technique was used in 822 patients (55%) and the Judkins technique in 676 (45%). Saphenous vein grafts were studied in 12% or 180 cases. The amounts of contrast medium usually used were 4 cc for right coronary artery injection and 6 cc for left coronary artery and saphenous vein graft injections over 2 seconds. No acute coronary artery dissections, one coronary occlusion (0.067%), one death (0.067%) in a patient with greater than 90% left main coronary obstruction, and three (0.20%) acute myocardial infarctions occurred. We conclude that power injection is a safe technique for coronary angiography. This technique is easier to use, could improve the quality of coronary angiography, and may actually be safer than hand contrast medium injection.

Adult↗
PubMed1979

Pericardial tamponade in systemic sclerosis (scleroderma).

The frequency of pericardial disease in scleroderma found at necropsy in high. The clinical recognition of pericarditis with or without effusion is rare and tamponade with haemodynamic impairment is exceptional. Three patients with scleroderma presented with an acute syndrome of dyspnoea, chest pain, and cardiomegaly requiring pericardiocentesis for relief of pericardial tamponade. One patient died. The mechanism of the pericardial effusion remains unknown. The haemodynamic data recorded from one patient suggested that pericardial fibrosis in scleroderma may predispose to pericardial tamponade.

Adolescent↗
PubMed1977

Exertion-induced rhabdomyolysis with acute renal failure and disseminated intravascular coagulation in sickle cell trait.

From 1970 to 1974, among thousands of trainees seen at two large military installations who were subjected to the same physical and environmental stresses, only four recruits were hospitalized because of acute exertional rhabdomyolysis, renal failure and coagulopathy. The illness followed the performance of vigorous exercise. These four patients had sickle cell trait. In an attempt to explain this association, the data in these four cases are summarized. The hypothesis is then developed that rhabdomyolysis and endothelial damage, terminating in severe coagulopathy, may more likely occur in patients with sickle cell trait who are subjected to virorous physical exertion.

Acute Kidney Injury↗
PubMed1977

Group Y meningococcal disease in United States Air Force recruits.

Between 1971 and 1974, group Y meningococcal disease developed in 88 Air Force recruits; 68 had primary bacterial pneumonia. None of the patients with primary pneumonia had the stigmata of meningococcemia or meningitis. Patients with pneumonia responded well to small doses of parenteral penicillin. Ten patients had meningococcemia, and six had meningitis. Pneumonia, therefore, predominated over meningococcemia and meningitis 4:1. Skin lesions were rare in patients with meningococcemia but frequent in those with meningitis; otherwise, these clinical syndromes were similar to group B and C meningococcal disease. There was only one death, a patient with known preexisting leukopenia.

Adult↗
PubMed1976

Pancytopenia and "caillary leak syndrome" with infectious mononucleosis.

A 19-year-old man with documented infectious mononucleosis presented with pancytopenia and a megaloblastic bone marrow. He developed a "capillary leak syndrome" with an expanded plasma volume of 9,290 ml and normal right heart and pulmonary artery pressures. The patient had a dramatic recovery after corticosteroid therapy.

Adult↗
PubMedDate not supplied

Hypothyroidism presenting as a polymyositis-like syndrome. Report of two cases.

Two patients with proximal muscle weakness and marked elevations of serum muscle enzymes were initially believed to have polymyositis; however electromyography and muscle biopsies were normal. Both patients were subsequently found to have hypothyroidism. Each regained her muscle strength, and serum enzymes normalized with thyroid hormone replacement. Because muscle weakness and an elevated creatine phosphokinase occur in most patients with hypothyroidism, thyroid dysfunction must be considered in the differential diagnosis of polymyositis.

Adult↗