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Biomedical subjects

G M Kenny

Publications and source records attributed to G M Kenny.

At least 19 recordsLinked to original sources

The prevalence of personality disorders in 210 women with eating disorders.

BACKGROUND: The purpose of this study was to assess the prevalence, reliability, and predictive value of comorbid personality disorders in a large sample of 210 women seeking treatment for anorexia nervosa (N = 31), bulimia nervosa (N = 91), or mixed disorder (N = 88). METHOD: All subjects were interviewed using the Structured Interview for DSM-III Personality Disorders as part of a longitudinal outcome study of eating disorders currently underway at Massachusetts General Hospital. RESULTS: Of the 210 subjects, 27% had at least one personality disorder; the most commonly observed was borderline personality disorder in 18 subjects (9%). The highest prevalence of personality disorders was found in the anorexia nervosa/bulimia nervosa group at 39%, followed by 22% in the anorexics and 21% in the bulimic sample. We found statistically significant differences regarding the distribution of personality disorders across eating disorder groups. The dramatic personality disorder cluster was differentially distributed across groups; this finding was accounted for by higher rates of borderline personality disorder in the bulimia nervosa and anorexia nervosa/bulimia nervosa groups than in the anorexia nervosa group. The anxious personality disorder cluster was differentially distributed across groups with higher rates in the anorexia nervosa and anorexia nervosa/bulimia nervosa samples. Those subjects with a comorbid personality disorder had a significantly slower recovery rate than those without a comorbid personality disorder. CONCLUSION: The prevalence of personality disorders is not high in treatment-seeking women with eating disorders compared with previously studied samples. The greatest frequency of comorbid personality disorders is in the anorexia nervosa/bulimia nervosa group; this subset also had longer duration of eating disorder illness and much greater comorbid Axis I psychopathology compared with the rest of the sample. Future studies should address whether personality disorders have predictive value in the long-term course and outcome of eating disorders.

Adolescent

Transrectal ultrasound study of prostate.

Better detection of prostate cancer has been achieved in this study of a limited number of patients by the combined use of digital rectal examination and transrectal ultrasound examination. With more experience and modern equipment improved detection of prostate cancer can be expected.

Aged

Ether cystitis.

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Adult

Urogenital aspects of actinomycosis.

Urogenital actinomycosis has always been a rare entity, limited to a few cases in any series. Treatment is highly successful but diagnosis remains elusive owing to low incidence, variable clinical picture, and biopsy and culture uncertainties. The general incidence of actinomycosis is believed to be decreasing in recent years but many infections may go undiagnosed while being suppressed or cured by conventional antibiotic therapy given for other resons. Our incidence of 4 cases of genitourinary and abdominal actinomycosis occurring in a 1-year period is highly unusual but the reasons remain speculative. Prior operation, abortion and induced infection via an intrauterine device were probably contributory. Whatever the case, if our experience is shared by others, genitourinary actinomycosis deserves more prominent diagnostic consideration in the future.

Actinomycosis

The treatment of rejection. A trial of acetylsalicylic acid, dipyridamole, and heparin.

Serial studies of platelet and fibrinogen survival were performed in 26 nonimmunosuppressed dogs after allogenic renal transplant operations. Treatment with acetylsalicylic acid, dipyridamole, and heparin failed to improve the selective platelet destruction which occurred in untreated animals, and it did not improve postoperative longevity. There was a high incidence of postoperative wound and intrarenal hemorrhage after heparin treatment. These results are consistent with the hypothesis that platelet destruction is a consequence rather than the cause of acute graft rejection, and it is concluded that antithrombotic therapy is not of practical benefit in preventing acute rejection.

Animals