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Biomedical subjects

G M Fara

Publications and source records attributed to G M Fara.

At least 55 records · Page 3Linked to original sources

A multicentric study for serotyping and susceptibility to antibiotics of pneumococci in Italy.

A multicentric study of the incidence of pneumococcal serotypes was recently carried out in five different geographical areas in Italy. Two hundred and sixty-seven strains were typed using the quellung reaction with monospecific antisera, but only 28 of these were isolated directly from the site of infection. The most frequent serotypes were 19, 6, 3, 9, 4, 1 and 18 without remarkable differences regarding the area, age of patients and site of isolation. It was found that 60.3% of the serotypes isolated from all sources and 67.8% of those isolated from the sites of infection are contained in the currently used antipneumococcal vaccine. Antibiotic resistance was found versus aminoglycosides (34.9%), tetracycline (28.3%), chloramphenicol (5.2%) and penicillin (3.3%). Cefoxitin appeared to be the antibiotic to which the pneumococci were most susceptible. Only two types, 19 and 16, resulted resistant to all the antibiotics.

Anti-Bacterial Agents↗

Immunity status against poliomyelitis in persons 13-14 years old living in Rome.

The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended.

Adolescent↗