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Biomedical subjects

G Lorette

Publications and source records attributed to G Lorette.

260 records · Page 15Linked to original sources
PubMedDate not supplied

[Treatment of bilharziasis due to Schistosoma mekongi with praziquantel].

After a review of the mechanisms of anti-schistosomal activity of praziquantel and the treatment of Schistosoma mekongi with this drug, the authors report two cases of Schistosoma mekongi treated with praziquantel with failure. Rectal mucosa biopsies are performed and eggs are present. Light microscopic, electron microscopic and on ultra-thin sections examination of these samples don't reveal morphological alterations of Schistosoma mekongi eggs after treatment.

Adult↗
PubMedDate not supplied

[Diffuse hemangiomas of the skin and gastrointestinal tract. A case of blue rubber bleb naevus (author's transl)].

The authors report the case of a 33-year-old patient with 109 skin hemangiomas of the blue rubber bleb naevus type, accompanied by angiomas of the mucosa of the gastrointestinal tract. Bleeding of the angiomas caused anemia. This case was apparently sporadic. The authors recall the clinical, histological and ultrastructural features of this rare disorder. Histology can help to differentiate BRBN from glomangioma.

Adult↗
PubMedDate not supplied

[Malignant fibrous histiocytoma with granular cells].

This report describes a malignant tumor of soft tissue which combined granular cells with an histologic pattern of malignant fibrous histiocytoma. Immunohistological and ultrastructural studies were performed. Neo-plastic cells were devoid of S-100 Protein but contained lysozyme. Ultrastructural findings showed granular cells containing numerous lysosomes and non-granular cells exhibiting fibroblastic and histiocytic differentiations. This lesion prompts us to consider either a malignant granular cell tumor or a malignant fibrous histiocytoma.

Aged↗
PubMedDate not supplied

[Dyskeratosis congenita Zinsser-Cole-Engman form. Report of two affected brothers (author's transl)].

Cutaneous pigmentation, lingual leukoplasia and dystrophic changes of nails are present in the two cases. The other clinical manifestations are dental alterations, epiphora, loss of dermal ridges of the pulp with hyperhidrosis, atrophic skin of the dorsum of the hands. Dysphagia and bone marrow hypoplasia are present in one case. The proband (case 1) has normal values for the following: hemoglobin electrophoresis, pyruvate kinase, marrow and blood chromosome analysis. Biopsy of pigmented skin showed an atrophic epidermis with orthokeratotic-hyperkeratosis; in the higher dermis there were several melanophores. Multiple layers of vasal lamina are seen under electron microscopy. The parents and the two daughters are free of clinical or hematologic manifestations. The mother and her two affected sons have A1-BW 27 HLA haplotype. X-linked transmission is discussed.

Adolescent↗