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Biomedical subjects

G Linss

Publications and source records attributed to G Linss.

At least 73 records · Page 4Linked to original sources
PubMed1981

[The measurement of airway resistance during exercise by body plethysmography before and after application of asthma-protective drugs (author's transl)].

The behaviour of airway resistance under and after physical exercise up to 75 watt was investigated in 70 persons. In this test the airway resistance of subjects with healthy lungs and patient suffering from bronchial hyperreactivity does not show any significant changes. Patients with manifest obstructive ventilation disorders may be divided into two groups: in the major group (preponderant patients with a chronic bronchitis) the airway resistance decreases under exercise and reaches not the starting level up to the 8th minute after finishing exercise. In the minor group with the clinical picture of asthma the airway resistance increases during and after exercise and reaches it maximum in the 4th minute of recreation. In the same group the oxygen partial pressure decreases under exercise but on the average remains within the age-dependent reference-range. With the drugs disodium cromoglycate ("Intal"), Ketotifen ("Zaditen") and ipratropium bromide ("Atrovent") it's possibly to reduce the exercise induced increase of airway resistance; in comparison ipratropium bromide has the best effect.

Adult↗
PubMed1980

[Expert opinion in chronic arterial hypertension].

The expert opinion on chronic arterial hypertension contains several problems, such as influence on choice of the profession and change of the profession, judgement of the traffic ability, judgment of the ability for military service, judgment of connective questions and judgment of capability of earning a living. Of particular importance is the expert opinion the following criteria shall be submitted to a complex valuation: etiology and degree of severity, therapeutic influencibility, physical efficiency, use of rehabilitation measures, side-effects of medicaments, prognosis of hypertension, taking into consideration the natural course and the complications after sufficiently long time fo observation and under optimum use of therapeutic and rehabilitative measures.

Employment↗
PubMed1980

[The heart in hypertension].

After indications to the great epidemiologic importance of hypertensive heart disease and its relationship with the ischaemic heart disease several results are reported collected during the past 10 years by examinations of more than 500 patients for early diagnosis of cardiac insufficiency in hypertension. The methods of microcatheterization of the pulmonary artery and radiography have been used (even under ergometrical exercise) as well as the calibrated apex cardiography and the echocardiography. For the practising physician a classification of hypertensive heart disease with 4 phases or forms is proposed. The paper ends with a demonstration of the close relationship between prevention and treatment of hypertension as well as between hypertensive and ischaemic heart disease at the same time in a sense of the integrative role of heart insufficiency.

Cardiomegaly↗
PubMed1980

[New viewpoints on the pathophysiology and pathogenesis of arterial hypertension].

The pathophysiology and pathogenesis of the arterial hypertension can be explained from disturbances in the meshed regulating circle. Newer knowledge concerns the noradrenergic transformation of the excitation at the synapse. Concerning the humoral pressor systems we refer to the tonin-angiotensin-system, it is furthermore emphasized the disturbance in the sodium-potassium-transport on the membrane. The depressor systems -- prostaglandins, kallikrein-kinin-system -- will in future certainly bring newer knowledge concerning their participation in the pathogenesis of arterial hypertension. The practical importance of such findings should be taken into consideration in the formation of the long-term therapy of arterial hypertension.

Angiotensin II↗
PubMed1980

Echocardiography [UCG] in hypertension. Myocardial performance comparison with controls and sportsmen.

Thanks to a number of parameters available, mean velocity of fibre shortening (mVCF), fibre shortening (FS%), ejection fraction (AF), stroke volume (SV), enddiastolic volume (EDV), echocardiography (UCG) is a non-invasive and well reproducible technique for examining the functioning of the heart. The UCG results obtained for 93 pre-treated male non-congestive hypertensives were compared with those obtained for 75 normotensives and 21 endurance sportsmen. In spite of the increasing degree of HT (WHO standards), the cases studied did not show a statistically significant decrease in the myocardial function. This study reveals that in general the heart of a hypertensive does not yet show at rest an overall functional loss. Compared with the left ventricular mass, however, a trend towards reduced performance can be seen, particularly when compared with sportsmen having a hypertrophy of a similar degree.

Adult↗
PubMed1979

[A-wave in calibrated apex cardiogram in hypertension. Studies during rest and after exertion].

Apexcardiographic examinations were carried out of 86 hypertensive patients without clinically manifest heart failure. The amplitude of the wave a (or the per cent fraction of the wave a of the total amplitude) and the maximal rate of wave rise, df/dta were statistically significantly higher in the hypertensive patients than in normal subjects. The findings are interpreted as a manifestation of an increased left ventricular rigidity and of an increased atrial contractility in hypertensive patients. No correlation was found between the apexcardiographic indicators checked and the indicators of the cardiac pump function. In 46 hypertensive patients, in addition, a dynamic exercise test was performed (50 W for 6 min); 1 minute after cessation of exercise an apexcardiogram was recorded. An increase in the a/T quotient (greater than or equal to 5%) was found in 20; a decrease (=5%), in 10; and no change (less than +/- 5%), in 16 hypertensive patients. The postexercise apexcardiographic changes had no correlations with haemodynamic changes occurring during exercise.

Adolescent↗
PubMed1976

[Necrobiosis lipoidica diabetricorum and serum lipids].

Necrobiosis lipoidica diabeticorum is briefly described. Its high coincidence with hyperlipoproteinaemia in casuistic reports from the literature as well as in about half of the 22 cases observed in our clinic can be taken in favour of possible relations between these conditions. Disturbances of fat metabolism may even be considered important for pathogenesis of necrobiosis in general, the more as at least no optimally regulated fat and carbohydrate metabolism can be achieved by best therapeutic control of carbohydrate parameters in juvenile diabetics. Microangiopathia diabetica seems to exist from the very beginning of diabetes mellitus and may ne a basic etiologic prerequisite for the development of necrobiosis. Topical conditions of certain body regions are said to take part in final precipitation of necrobiotic spots.

Adult↗
PubMed1975

[Anamnesis as a screening method for cardiovascular diseases].

In general the anamnesis meets all requirements which are put to a screening method; however, special problems arise when the anamnesis is made by means of a questionnaire. The team which gives the report had projected a questionnaire for 8 cardiovascular groups of diagnosis (ischaemic heart disease, hypertension, functional, inflammatory and pulmonary heart disease, disturbances of the peripheral arterial blood supply, cerebrovascular insufficiency and venous diseases). This questionnaire was reduced and qualified and tested on test persons of a Berlin enterprise. A final judgment concerning the use of the anamnesis as screening method cannot be given at present. However, it limns oneself already that it is possible with its help to establish many endangered persons and patients and to subject them to the primary and secondary prevention.

Cardiovascular Diseases↗