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Biomedical subjects

G Lindsay

Publications and source records attributed to G Lindsay.

51 records · Page 3Linked to original sources
PubMed1985

Temocillin in the treatment of serious gram-negative infections.

Temocillin was used to treat 32 patients with proven or suspected infection caused by aerobic Gram-negative bacteria. 25 of these patients were assessable on clinical and bacteriological grounds. All 25 were either cured or improved, although in 5 patients with urinary tract infection there was relapse of infection or reinfection following the cessation of therapy. Clinical improvement was usually rapid and no serious side effect was noted. Temocillin would thus appear to be an effective and safe agent for the treatment of bacterial infection caused by aerobic Gram-negative organisms.

Adult↗
PubMed1979

Away from it all?

Explore the source record for details and available documents.

Community Health Nursing↗
PubMedDate not supplied

Selective decontamination of the colon before elective colorectal surgery. West of Scotland Surgical Infection Study Group.

The controversy over the route of administration of antibiotic prophylaxis in patients undergoing elective colorectal operations persists for oral, parenteral, and a combination of the two routes. The oral antibiotics commonly administered for colorectal prophylaxis, neomycin and eythromycin base, are not absorbed in the gastrointestinal tract (GIT). However, the 4-fluoroquinolones are absorbed in the upper GIT and are excreted in part by the colonic mucosa. Their action is then to remove, or severely depress, the gram-negative aerobic bacilli leaving the anaerobic flora unaffected. This action is the principle of selective decontamination. We have assessed the efficacy of oral ciprofloxacin in a prospective randomized clinical trial in which all patients received piperacillin 4 g i.v. as single-dose parenteral prophylaxis. A group of 327 evaluable patients were randomized to receive ciprofloxacin 500 mg b.i.d. with the preoperative cathartic (group OA, n = 159) or no oral antibiotic (group NOA, n = 168). Postoperative wound infection occurred in 18 (11.3%) patients in group OA and 39 (23.2%) patients in group NOA (chi 2 = 7.2, p = 0.007). Operation-related infection of any type occurred in 23 (14.5%) patients in group OA compared with 55 (32.7%) in group NOA (chi 2 = 14.0, p = 0.0002). The median postoperative hospital stay was 11 days (interquartile range 4.5 days) for group OA and 12 days (interquartile range 8 days) for group NOA (Mann Whitney U test, p = 0.005). Ignoring the treatment group, the median postoperative hospital stay was 17 days (interquartile range 10 days) for infected patients and 11 days (interquartile range 4 days) for those not infected.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Is nurse-supervised exercise stress testing safe practice?

OBJECTIVE: Nurses have been performing exercise stress tests (EST) without medical supervision since 1978 in our hospital-based cardiac rehabilitation unit. This study was conducted to examine the incidence of cardiovascular complications and to describe the competency-based training program for the nurses performing the EST. DESIGN: Descriptive, retrospective audit of prospective data. SETTING: Single comprehensive cardiac rehabilitation center in a large tertiary referral hospital in western Sydney, Australia. SUBJECTS: Seventeen thousand, four hundred and sixty-seven patients were included in this study over a 12-year period. METHOD: Data were collected on all ESTs performed by the cardiac rehabilitation nurses from January 1986 to December 1997 in relation to serious cardiovascular complications and other EST parameters. RESULTS: In this study, 17,467 ESTs were performed on 5054 patients who had 6273 separate presentations. The most common entry diagnosis was after an acute myocardial infarction (50%). The mean age was 58 +/- 10.5 years (range 15 to 87 years; 80% male). The left ventricular ejection fraction (n = 2822) was 49% +/- 14%. In a subgroup analysis of 14,454 patients, 14% had a positive EST (ST segment >1.9 mm depression). There were no deaths associated with the EST, and there were 13 major complications in 12 patients. This figure included no cardiac arrests, 11 episodes of conscious sustained ventricular tachycardia, 1 reinfarction, and 1 mitral valve rupture, representing a 0% mortality rate and a 0.075% major morbidity rate. CONCLUSION: This study shows that nurse-supervised EST of higher risk patients in the hospital-based cardiac rehabilitation setting has been a safe practice from a mortality and morbidity rate perspective. This finding may be accounted for by the high training standard and reaccreditation of the nurses on the advanced practice of performing EST.

Adolescent↗
PubMedDate not supplied

Setting up a helpline on heart disease.

This article describes how the first nurse-led national telephone helpline for the prevention of coronary heart disease (CHD) was set up and presents the results after the first year of operation. The free service was well received. Most callers were seeking advice on CHD prevention for the first time and traditional risk factors and general healthy lifestyle advice remained major areas of concern.

Adult↗
PubMedDate not supplied

A study of nurse-led shared care for coronary patients.

A randomised controlled study of nurse-led shared care of patients awaiting coronary artery bypass surgery led to significant improvements in patients' care management. Here, we summarise the study's findings.

Coronary Artery Bypass↗
PubMedDate not supplied

Implementing research in nurse-led care.

In response to research showing that people waiting for cardiac surgery had a high prevalence of uncorrected coronary heart disease risk factors, a nurse-led shared care scheme was developed. A randomised controlled trial of the service demonstrated significant improvements in risk factors among the intervention group. The study is used as an example of how research findings have been used to identify an area for practice development.

Cardiac Surgical Procedures↗