Search PubMed⌕ Search

Biomedical subjects

G Li Destri

Publications and source records attributed to G Li Destri.

At least 37 records · Page 2Linked to original sources
PubMed1989

Non-operative treatment in the management of traumatic lesions of the spleen--a new kind of therapy?

The onset of severe episodes of sepsis in splenectomized patients has induced surgeons to perform conservative operations in order to save at least partial functioning of the spleen. Recently, great interest has been focused on the non-operative treatment of traumatic lesions of the spleen, which involves careful and continual observation of patients with splenic nauma to monitor their course towards recovery. This method of treatment was recently adopted by our department for two patients whose case histories are presented herein. Non-operative treatment is suitable only in strictly selected subjects, who must be carefully monitored in an intensive care unit where constant examination and sophisticated diagnostic procedures are readily available. Although the non-operative treatment of splenic trauma is not new, it is only recently that its management, programming and role have been updated.

Adult↗
PubMed1989

Pancreas transplantation in the rat using Lee's technique: a reliable model in experimental microsurgery.

Numerous unresolved problems, both technical and immunological, in pancreas transplantation stimulate experimental studies. Dogs have been routinely used in experimental studies but today rats are more commonly used. However, pancreas transplantation in the rat presents complex technical problems and requires a good knowledge of microsurgical techniques. In 1983 Squifflet undertook an experimental study aimed at evaluating the technical aspects of pancreas transplantation in the rat and calculating the success rates using different methods. The comparison of four methods revealed to our surprise that 100% of the rats operated on using Lee's technique had complications, with a 0% survival rate. In our study we report our experience using Lee's technique which we had the opportunity of mastering directly under the supervision of Professor Lee. We performed 100 pancreas transplantations using Lee's technique and divided our study in two phases. In the first phase we performed 70 pancreas transplantations and overall survival, after 1 week, was 42 rats (60%). In the second phase on 30 rats diabetes was induced by administering 70 mg/kg of streptozotocin. These 30 diabetic rats underwent pancreas transplantation and overall survival, after 1 week, was 25 (83.3%). We believe that our successful survival rates could probably be explained by the close collaboration between Lee and our department. Moreover, we noted the importance of constant training in obtaining better results, and in our opinion Lee's technique of pancreas transplantation is a reliable experimental model which can be used to resolve problems linked to pancreas transplantation.

Animals↗
PubMed1989

[Motor disorders of the esophagus in gastro-esophageal reflux disease].

The Authors report their experience in the study of oesophageal motor abnormalities in patients with gastroesophageal reflux disease. By an electromanometric test in 50 subjects (20 healthy volunteers and 30 patients with oesophagitis), they evaluated the results concluding that: 1) LES low pressure is correlated significantly with oesophagitis; 2) oesophageal peristaltic dysfunction could be the effect of oesophagitis rather than its cause.

Adolescent↗
PubMed1989

Cholecystectomy and colorectal cancer: an improbable correlation.

Several scientists have mentioned the cause and effect relationship between cholecystectomy and onset of large bowel cancer but have reached no real conclusions since the valid theoretical premises have often been denied by clinical series. In this report also, no statistically significant correlations between cholecystectomy and colorectal cancer have been found. It is suggested that this operation is only an epiphenomenon of a different etiologic phase, for instance, type of diet.

Cholecystectomy↗
PubMed1988

Radio-hyperthermia for subcutaneous metastasis of hemangiopericytoma of the mediastinum: case report.

Hemangiopericytoma is a rare type of neoplasia originating from the Zimmermann pericytes and can arise in numerous sites. As it is difficult to correlate the histologic aspect with the prognosis, it was considered advisable to take account of other factors such as age and tumoral site. Aggressive surgery followed by irradiation therapy is suggested as the most suitable management. Hyperthermia also was adopted in treating subcutaneous metastasis, but its role has yet to be fully defined.

Age Factors↗
PubMed1988

Leiomyosarcoma of the spermatic cord. Case report and review of the literature.

An additional case of leiomyosarcoma of spermatic cord which brings the total reported number to 49, is described. The case is compared with the others and further data on histogenesis and histological behaviour of the tumor, are given. Surgical treatment and role of radiotherapy and chemotherapy, are discussed.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1986

Doppler test after microvascular anastomoses and evaluation of somatostatin administration in segmental canine pancreas autotransplantation. A preliminary study.

Segmental pancreatic transplantation still involves a certain number of possible technical complications. The experimental studies in dogs reported here evaluate the effectiveness of vascular microanastomoses using doppler velocimetry in two groups of dogs which underwent segmental pancreatic autotransplantation. One group was protected by intraoperative somatostatin infusion, while the other was kept as control. The obtained results indicate that the doppler-test revealed early vascular complications (2/20 animals) and that somatostatin administration may play a major role in the prophylaxis of pancreatitis.

Animals↗
PubMed1981

[A rare case of sigmoidoduodenal neoplastic fistula (author's transl)].

The clinical case of a patient with sigmoidoduodenal neoplastic fistula is taken as the starting-point for a review of the relevant literature. The great rarity of fistulisation of a sigmoid tumour of the 4th portion of the duodenum is stressed. A clinical definition of the disease is followed by a discussion of the various methods of surgical treatment, with emphasis on the problem presented by reconstruction of the duodenum owing to its anatomosurgical difficulties.

Adenocarcinoma↗