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Biomedical subjects

G Lefort

Publications and source records attributed to G Lefort.

98 records · Page 6Linked to original sources

Hematologic values of fetal blood obtained by means of cordocentesis.

Fetal blood values were evaluated from 541 cordocenteses. Simple regressions were used to find a correlation between blood values and gestational age. We found a linear increase in hemoglobin concentration and hematocrit throughout gestation; a linear decrease of the mean corpuscular volume with the gestation was evidenced as a regular decrease in mean corpuscular hemoglobin. Lastly, the mean corpuscular hemoglobin concentration was constant during the gestation; a linear increase of the platelet count and the nucleated cells was also evidenced. We suggest that each fetal medicine unit should have its own reference ranges. It will permit to accurately diagnose fetal infection, fetal anemia, or any fetal disease where alterations of hematopoiesis have been described.

Cordocentesis↗

[The utilization of small repeated doses of iodine 131 in the treatment of Graves' disease. Results (author's transl)].

In graves' disease small amounts of radioactive iodine administered repeatedly on a monthly basis depending on the progress of the disease is a method whose effectiveness we have studied on 192 cases over a period of 3 to 7 years. Relapses (4 %), failures (11 %) permanent hypothyroidism (24 % after 7 years) and the duration of the active stage have been collated with different clinical or biological parameters in order better to define the main factors that determine the course and prognosis. The size of the goitre and the presence of antithyroglobulin antibodies are among the most significant.

Antibodies↗