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Biomedical subjects

G Lazzari

Publications and source records attributed to G Lazzari.

At least 37 records · Page 2Linked to original sources

[Ultrasonographic findings and integration with computerized tomography in pathology of the abdominal wall].

Ultrasonography (US) plays a major role in the study of the anterior and lateral abdominal wall. Our experience refers to 150 patients examined over a 5-year period, who were divided into two groups according to disease etiology: 72 patients suffered from iatrogenic and 78 from non-iatrogenic conditions. The first group was mainly composed of alterations caused by anticoagulation therapy, e.g., hematomas, and recent or previous surgery, i.e., 19 incisional hernias and 19 inflammatory-abscess processes. The second group included above all 32 cases of abdominal wall hernia, 18 neoplasms, 13 traumas with abdominal wall involvement only and 12 inflammatory processes. US yielded valuable pieces of information to diagnose iatrogenic conditions, even for small or non-relevant conditions. Moreover, US allowed non-iatrogenic conditions to be located and identified, accurately demonstrating abdominal wall layers involvement. US was also very useful in the patients whose physical examination is of no use or difficult, e.g., in the patients with much pain and trauma or obese patients. CT was used in selected cases only, as a complement to US, when a more detailed spatial assessment of wide or deep lesions was necessary.

Abdominal Muscles↗

[Ultrasonographic evaluation of the sciatic nerve and thigh trauma].

This study was aimed at studying the normal morphology of the main extrapelvic trunk of the sciatic nerve, its average size and its anatomo-topographic relationships by means of high resolution US. The involvement of the sciatic nerve in traumas was also investigated. The lower gluteal region and the posterior aspect of both thighs were examined in 30 healthy subjects and in 11 patients with recent or previous traumas. The sciatic nerve is clearly demonstrated, on US images, between the biceps femoris muscle and the semimembranosus and semitendinosus muscles. The average dorsoventral diameter of the nerve is 6.4 mm at the upper third and 4.8 mm at the middle third of the thigh, while its average transverse diameter is 11.8 mm at the middle third of the thigh. In traumas, US demonstrated compression and displacement of the sciatic nerve in 6 recent hematomas and in 2 hypertrophic ossei calli of the femoral diaphysis. In 2 osteomyelitis cases with a posterior thigh fistula, US showed sciatic nerve involvement by the phlogistic process. Moreover, US allowed an old thick thrombosis of a satellite vein of the sciatic nerve to be depicted. In conclusion, the present study has demonstrated that US not only clearly depicts the sciatic nerve but also provides accurate information on its involvement in recent or previous traumas.

Adolescent↗

Centrifugal elutriation of porcine oocytes isolated from the ovaries of newborn piglets.

A two step enzymatic procedure for the isolation of ovarian follicles and oocytes at early stages of development from the ovaries of newborn piglets was devised. The isolated oocytes were then separated from the overwhelming majority of the ovarian somatic cells using a centrifugal elutriation system. Twenty to thirty thousand oocytes were routinely collected after elutriation of the cell suspension derived from a pair of ovaries. In the enriched fraction the ratio of oocyte:somatic cells was between 1:1 and 1:3. The validation of the method as an efficient procedure for the isolation of a large, viable, and highly enriched population of oocytes at early stages of development was provided by uptake studies carried out after each step of the isolation and separation technique and by a comparative analysis of the pattern of structural proteins of the enriched fraction and of fully grown porcine oocytes. The results confirmed that the isolated cells were actually oocytes at early stages of development and that they were viable throughout the entire procedure.

Animals↗

[Echographic evaluation of abscess pathology in superficial soft tissue. Personal experience].

Sonography is currently considered a very useful technique for the study of inflammatory-abscess conditions in superficial soft tissues. The authors report their experience with US in the study of 22 patients. In 15 of them a comparison was made with X-ray findings, in 4 with fistulographic and in 2 with CT results. US allows the abscesses to be evaluated in both their morphological structure and anatomical topography. US has proven especially useful in correctly evaluating both complete and incomplete fistulas, as well as in revealing foreign bodies. The US pattern of an abscess often confirms clinical diagnosis for it supplies further and more accurate information. Moreover, US sometimes allows an abscess to be demonstrated even when the latter was missed at clinics. However, the differential diagnosis with malignant neoplasm is difficult and sometimes a decision can be made only by means of other diagnostic imaging modalities.

Abscess↗

[Echographic evaluation of lymphadenopathies of the abdomen].

The US findings are reported of 91 cases of abdominal lymphadenopathy examined by either histological or instrumental check-up, or follow-up. Adenopathies were classified according to etiology, which was lymphomatous or leukemic in 19 cases, metastatic in 56, and reactive or inflammatory in 16. Lymph node involvement was most frequent in porta hepatis, periportal and peri-aortocaval locations. US findings allowed a diagnostic approach to be planned based on number, size and morphology of adenomegalies, as well as on the involved lymph nodes. In the porta hepatis and periportal areas, adenomegalies were most often due to neoplastic metastases of the alimentary canal, and to inflammatory-reactive disorders. Adenopathies in the peri-aortocaval area were most often due to systemic and to severe neoplastic metastases having their primary location even out of the alimentary canal.

Abdomen↗

[Double-contrast gastrography and gastroscopy in the diagnosis of gastric polyps. Personal experience].

Gastric polyps are benign tumors which have been less uncommonly detected in recent years, due to the refinement of both radiologic and endoscopic investigations. From 1981 through 1985 gastric polyps were detected in 102 patients (1.9%) out of 5368 radiologic examinations. In the same period, 98 cases (3.3%) were detected out of 2942 endoscopic examinations. The comparison of data in these two series shows a superimposition. Despite an increased percentage of endoscopic findings (to some extent due to previous radiologic reports), the authors assert the diagnostic efficacy of double contrast radiologic investigation as a first approach to benign polypous lesions of the stomach. As far as histology is concerned, a clear prevalence is shown of hyperplastic versus adenomatous polyps (90 and 8 cases respectively).

Adolescent↗

Hodgkin's disease developing in a patient with angioimmunoblastic lymphadenopathy with dysproteinemia--a case report.

The case of a woman presenting the clinical and pathologic phenomena of angioimmunoblastic lymphadenopathy (AILD) with dysproteinemia is reported. The patient developed lesions in the lymph nodes, skin, lungs, liver and spleen, and her response to steroid and cyclophosphamide therapy was poor. At autopsy, microscopic findings in the mediastinal and abdominal lymph nodes were consistent with the diagnosis of Hodgkin's disease. Whereas the development of immunoblastic lymphoma is frequent in AILD, Hodgkin's disease is far less common. It is argued that malignant lymphoma in AILD may be the consequence of chronically depressed lymphocyte functions.

Adult↗