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Biomedical subjects

G Lamas

Publications and source records attributed to G Lamas.

62 records · Page 4Linked to original sources

[Treatment of acquired stenosis of the external auditory canal].

Often difficult surgical problems are encountered during treatment of acquired stenosis of external auditory canal. Theses stenoses can be of tumoral, inflammatory or traumatic origin and are the cause of infectious complications related to epidermal retention. Even with the assistance of modern imaging procedures, preoperative investigation is not simple, precise details of lesions being obtained in greater detail during surgical exploration. Four stages are involved in surgical treatment: excision of lesion, reaming of bony canal and enlargement of auditory meatus, providing cover and maintaining graft in place. The CO2 laser can be useful for excision of lesion or possible postoperative recurrence, and adjacent pedicle flaps are best for covering site. Postoperative inflammatory episodes can be treated by infiltration of local corticoids. Whatever the result of these different techniques, long-term surveillance of these patients is essential.

Constriction, Pathologic↗

[Treatment of sequelae of basedowian exophthalmos].

Treatment of sequelae of ophthalmopathy of Basedow's disease, essentially exophthalmos, oculomotor disorders and upper eyelid retraction, is of particular importance because of the functional and esthetic problems presented. Improvement in the different symptoms can be obtained by surgical treatment, but patients must have been perfectly stable with respect to both the thyroid and ophthalmologic plan for at least 6 months. It marked exophthalmos exists this is treated initially by orbital enlargement. Oculomotor problems are then resolved and finally treatment is terminated by surgery to eyelids. Very satisfactory functional and esthetic results are obtained.

Exophthalmos↗

[Surgical treatment of temporomandibular joint dysfunctions by Myrhaug's technic. Apropos 60 interventions].

The treatment of the chronic diseases of the temporomandibular joint is always difficult. At one moment or another, surgical treatment is discussed, proposed and performed. Many operations have been described to make the temporo-mandibular joint recovering its normal movements. Both joints are involved in those movements, because the joint is symmetrical. Myrhaug's technique, described in 1951, consists in the resection of all the temporal condyle. This technique which respects the meniscus and all the chondro-fibrous system of the joint creates a permanent and reducible chronic dislocation of the joint. This paper is made to show that under an experience of more than 60 operations the authors can give all the details they use, with some modifications of the original Myrhaug's technique. The authors give their own results over 60 operations: there are more than 70% of good or excellent results, without any complication. For all the cases they have operated and they present, the follow-up is more than one year and some times more than ten years. They have not seen any late complication and the results have not been modified after all that time. The main indication of this technique is the temporomandibular joint dysfunction syndrome which affects more the female population. This syndrome is made of an association of pain, cracking, abnormal movements and subdislocations, but pain is only one of the symptoms. The same operation is very efficient to treat chronic subdislocations affecting one or both joints. This Myrhaug's technique operation is very simple without any complication in the post-operative days and give very good results.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

[Basal cell adenoma of the parotid. Apropos of a case with an ultrastructural study].

A case of Basal cell adenoma occurring in a 42 year-old woman is reported. Histological examination showed trabeculae of basaloid cells with thick Basal Membrane at the periphery. By Electron Microscopy most of the cells displayed numerous desmosomes and intracytoplasmic tonofilaments indicating epidermoid differentiation. In addition some glandular cells were observed. No myoepithelial cell were present. Electron Microscopy may be useful to differentiate basal cell adenoma from Adenoid cystic carcinoma which is made up of a majority of poorly differentiated cells.

Adenoma↗

Monthly intravenous pulse cyclophosphamide therapy in Wegener's granulomatosis.

OBJECTIVE: To study the long term effects of monthly intravenous cyclophosphamide therapy in Wegener's granulomatosis. METHODS: Fourteen consecutive patients with active Wegener's granulomatos treated with a first-line combination of high-dose prednisone and monthly intravenous pulse cyclophosphamide were retrospectively studied. RESULTS: One patient died from septicemia complicating severe leukopenia after the first pulse. At 8 months after instituting intravenous pulse cyclophosphamide therapy, failure was observed in 6 other patients. Between month 16 and 18, 2 other patients relapsed when the time between 2 pulses was lengthened. Five patients developed cyclophosphamide-related side-effects: infection (n = 2), amenorrhea (n = 1), alopecia (n = 2) and vomiting (n = 2). Except for one fatal infection, no major side-effect of intravenous cyclophosphamide therapy was observed. At the end of the study, all patients were off intravenous cyclophosphamide therapy with more than 6 months of followup. The 6 responders were in remission on low-dose prednisone or without treatment. CONCLUSION: A combination of high-dose prednisone and intravenous cyclophosphamide may achieve long-term remission in 42% of patients with Wegener's granulomatosis. Responders to intravenous cyclophosphamide therapy had less extensive disease than non-responders.

Adolescent↗