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Biomedical subjects

G Lacroix

Publications and source records attributed to G Lacroix.

31 records · Page 2Linked to original sources
PubMed1985

In vitro activity of enoxacin compared with norfloxacin and amikacin.

The in vitro activity of enoxacin was tested against 1000 clinical isolates of gram-positive and gram-negative microorganisms and compared with that of norfloxacin and amikacin. The MIC90 of enoxacin was 1 mg/l for Enterobacteriaceae, 2.6 mg/l for Pseudomonas aeruginosa and 6.2 mg/l or Staphylococcus aureus. The inoculum effect was minimal. The MICs and MBCs for Pseudomonas aeruginosa strains were significantly affected by the addition of calcium and magnesium ions. Synergy was occasionally observed between enoxacin and the antibiotics tested; antagonism was rare.

Amikacin↗
PubMed1982

Dry ashing, hydride generation atomic absorption spectrometric determination of arsenic and selenium in foods.

A dry ashing, flameless atomic absorption spectrometric method was evaluated to determine arsenic and selenium in foods. Samples were dry-ashed with Mg(NO3)2-MgO and dissolved in HCl. Selenate was reduced to selenite by boiling in 4N HCl. Selenate was reduced to selenite by boiling in 4N HCl, and arsenate to arsenite by treatment with KI. Hydrides of arsenic and selenium were generated by the addition of NaBH4 and were swept by nitrogen and hydrogen into a thermally heated silicate tube furnace. The detection limit was about 5 ppb for each element based on a 10 g sample. Analytical results obtained for several samples of NBS reference materials agreed with the certified values. The procedure was evaluated by another laboratory and results were satisfactory.

Arsenic↗
PubMed1980

Determination of arsenic in urine and feces by dry ashing, atomic absorption spectrometry.

A dry ashing flameless atomic absorption procedure was used to determine fish-arsenic in human urine and feces. Samples were dry ashed with Mg(NO3)2--MgO and dissolved in 6N HCl. Arsine was generated by the addition of NaBH4 and swept into a thermally heated silica tube furnace. Recoveries of several arsenic compounds added to samples ranged from 85 to 117%. The detection limit was about 3 ppb as for 10 g sample. Effects of the presence of common cations, anions and acids were studied.

Animals↗
PubMed1980

Comparison of three sample preparation techniques for determination of organic bromide and chloride in halogenated lipids by x-ray fluorescence spectroscopy.

Three sample preparation techniques--thin-film, solution, and cellulose pellet--were applied to the determination of bromide in brominated lipids by X-ray fluorescence spectroscopy. Using brominated vegetable oils of known bromide content it was demonstrated that the thin-film technique could result in erroneously high bromide contents, which could also vary with the amount of oil applied, depending on the solvent used. As solutions in hexane, slightly high bromide contents were observed at high concentrations. With the cellulose pellets, bromide contents similar to known values were observed. It was concluded that the cellulose pellet procedure, although more time consuming, and less convenient for ready recovery of sample, was the most suitable for organic bromide determination. Similar results were indicated for chlorinated oils.

Fats↗
PubMed1979

Recovery studies of selenium using dry ashing procedure with ashing aid.

A previously reported dry ashing procedure for the decomposition of marine samples prior to arsenic determination is demonstrated to be equally applicable to the analysis of selenium. Quantitative recovery of selenium as inorganic or organic compounds in a variety of plants and animal tissues is demonstrated using 75Se tracer and X-ray fluorescence techniques. The dry ashing procedure is simpler than the official AOAC method, which uses a mixture of H2SO4, HNO3 and HC10(4).

Animals↗
PubMedDate not supplied

[Cytologic study of giant cell tumors. Electron microscopy. Cyto-enzymology].

A cyto-enzymologic study of giant cells tumor revealed a high acid phosphatase activity in multi-nuclear cells (as in osteoclasts) and a very low alcaline phosphatase and peroxydase activity. Acid phosphatase was located in lysosom which were concentrated in definite cytoplasmic areas. The blood rate of this enzyme should be raised if it were excreted by the cells. Therefore a study of acid phosphatase blood rate could reinforce a diagnosis based on X-rays and a raising rate after surgery could help for early detection of recurrences.

Acid Phosphatase↗