Search PubMed⌕ Search

Biomedical subjects

G L Olsson

Publications and source records attributed to G L Olsson.

45 records · Page 3Linked to original sources
PubMed1984

An unusual complication following the removal of a neuroblastoma.

A 17-month-old girl had a neuroblastoma with high preoperative urinary excretion of norepinephrine and a manifest hypertension. She developed during and after surgery circulatory complications similar to those seen when a pheochromocytoma is removed without prior sympathetic blockade. This complication in connection with a neuroblastoma has not been described previously. This case points to the necessity of careful preoperative evaluation of the circulatory function in cases of neuroblastomas in children. The paediatric surgeon and the anaesthetist should take a preoperative sympathetic blockade into consideration.

Adrenal Gland Neoplasms↗
PubMed1984

Pain-free venepuncture. Effect of timing of application of local anaesthetic cream.

This study was designed to assess the effect of time on the analgesic effect of a local anaesthetic cream consisting of a mixture of 5% lignocaine and prilocaine. The cream and placebo were compared in a double-blind, randomized study in 114 children aged 4-17 years, with application times of 20 minutes and longer. A regression analysis revealed no difference in analgesic effect between cream and placebo when application times were less than 60 minutes. A cusum test showed that the effect of the cream became evident at about 60 minutes. Local adverse reactions consisted mainly of transient paleness of the skin, which did not constitute any clinical problem.

Adolescent↗
PubMed1984

Laryngospasm during anaesthesia. A computer-aided incidence study in 136,929 patients.

With the aid of a computerized anaesthetic record-keeping system, the incidence of laryngospasm during anaesthesia was studied, in order to quantify the risk of this complication. 136,929 patients given 156,064 anaesthetics were studied. There were 1,232 cases of laryngospasm recorded in 1,197 patients. The incidence of laryngospasm was calculated in subgroups characterized by age, sex, preanaesthetic conditions, premedication, anaesthetic technique, type of surgery and concomitant complication. An incidence exceeding 50 laryngospasms in 1,000 patients was observed when giving anaesthesia to children with bronchial asthma, with airway infection, in those who had a previous anaesthetic complication, during oesophagoscopy and when correction of hypospadias was performed. Extirpation of skin tumours and scars in males 50-59 years old was also accompanied by a similarly high incidence. Figures exceeding 25 laryngospasms in 1,000 patients were seen in the age group 1-3 months and in children undergoing appendicectomy, oral endoscopy and plastic surgery, when tracheal intubation had been performed and when a gastrointestinal tube was used. In the age group 50-59 years, an incidence exceeding 25 in 1,000 patients was seen when there had been preoperative airway obstruction and in females when the anaesthetic technique included spontaneous breathing and face mask, or apneic oxygenation. Dilatation of the anal sphincter and mediastinoscopy in males were also associated with an increased incidence of laryngospasm.

Adjuvants, Anesthesia↗
PubMed1983

Plasma concentrations of atropine after rectal administration.

The rectal administration of the premedication for children is often preferred in order to minimise discomfort. The appropriate dose of atropine when rectally administered is poorly documented. In this study six children weighing between 7.5 and 41 kg were given 0.02 mg atropine sulphate/kg rectally and four children were given the same doses intramuscularly. Plasma concentrations of atropine were analysed at several intervals after administration by a modified mass fragmentographic method accurate to 0.1 ng/ml. Peak plasma concentration of atropine, reached after 15 minutes, was 0.7 ng/ml, compared with 2.40 ng/ml reached after 5 minutes for the intramuscular route. The relation between intramuscular and rectal peak concentration was 3.2:1.

Atropine↗
PubMed1982

Pharmacological evacuation of the stomach with metoclopramide.

Children admitted for emergency operations because of trauma run a high risk of chemical aspiration pneumonitis syndrome. Fifty-eight children admitted for closed reduction of fractures and suturing of wounds were studied in a double-blind manner in order to see if metoclopramide could be of value in decreasing the risk of aspiration during anaesthesia. Metoclopramide given before anaesthesia proved to enhance gastric evacuation and could thus be of value in these situations. In addition, the study showed that the time from last oral intake until start of anaesthesia is of less importance then the type of trauma in prolonging the gastric emptying time and thus increasing the risk of vomiting and aspiration of vomitus into the lungs during anaesthesia.

Anesthesia↗
PubMed1981

[Circulatory disturbances during anaesthesia. A computer-aided analysis of 150,000 anaesthetic records 1967-1977 of the Karolinska hospital (Stockholm) (author's transl)].

The computerized anaesthetic record-keeping system at the Karolinska hospital at present (1980) contains anaesthetic records from approximately 200,000 cases. In order to evaluate the importance of circulatory disturbances during routine anaesthetic work, all records from 1967-1977 were searched for notes concerning complications. 5,996 anaesthetics were thus retrieved, having a total of 7,296 complications. This corresponds to an overall frequency of slightly more than 4 p. cent. Circulatory disturbances amounted to approximately 10 p. cent of all complications. Arrhythmias were common. Serious troubles i. e. circulatory arrests were very rare and these cases were studied individually. Differences in the frequency of complications as correlated to the preanaesthetic status of the patient including the risk group and diagnosis could be demonstrated. It is concluded that circulatory complications during anaesthesia exhibit patterns that can be analyzed from data collected during routine anaesthetic work provided a computerized anaesthetic record-keeping system is used.

Adolescent↗