Biomedical subjects
Publications and source records attributed to G L Hays.
A case of methemoglobinemia after injection of prilocaine in a patient who had Shwachman syndrome (Shwachman-Diamond syndrome) is presented. The report reinforces the need to be cognizant of dose/weight/mass relationships in patients receiving medications capable of oxidizing hemoglobin.
Hereditary epidermolysis bullosa is reviewed with emphasis on the junctional form (Herlitz-Pearson) (hereditaria letalis). A case report in which concurrent dental restorations and extractions were accomplished is presented.
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Exfoliative cytology smears from the buccal mucosa of patients with sickle-cell anemia, selected controls, and patients with other diagnosed anemias were studied for nuclear aberrations. A filar micrometer eyepiece was used to count the number of nuclei larger than 14 microns in mean diameter in a 500 cell count on each slide. Use of the Scheffe method of paired comparisons, disclosed that the number of cells larger than 14 microns in mean diameter, was significantly smaller in the control subjects, patients with microcytic anemia, and subjects with sickle-cell anemia than in the patients with megaloblastic anemia. Serum folate-deficient subjects had significantly more nuclei, per 500 cells, larger than 14 microns than control subjects or subjects on folate therapy. An explanation for the enlarged nuclei in smears from sickle-cell anemia patients is given. The possible use of this counting procedure to evaluate tissue folate status is suggested.
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Explore the source record for details and available documents.