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Biomedical subjects

G L Engel

Publications and source records attributed to G L Engel.

At least 55 records · Page 3Linked to original sources

Biomedicine's failure to achieve Flexnerian standards of education.

The central principle of medical education advocated by Flexner was mastery of the scientific method and its application to all dimensions of medicine, whether the bench laboratory, the bedside, or the social arena. Not Flexner but the biomedical model has been responsible for curricular designs that have under stressed the application of the scientific method to clinical data and the more person-oriented, psychosocial dimensions of illness and patient care. Flexnerian standards of medical education have yet to be achieved.

Curriculum↗

Psychologic stress, vasodepressor (vasovagal) syncope, and sudden death.

Giving up in the face of emotional arousal and psychologic uncertainty are conditions conducive both to vasodepressor syncope and sudden death. Under such circumstances there may be simultaneous activation of two emergency biologic regulatory systems, flight-fight and conservation-withdrawal. In the healthy person this may result in vasodepressor syncope, benign arrhythmias, or both. In the presence of factors lowering the threshold for conduction disturbances, dangerous arrhythmias and sudden death rather than, or as well as, vasodepressor syncope may result. Although active myocardial damage by itself may provide the necessary and sufficient conditions for lethal arrhythmias, psychic uncertainty must be considered an additional risk factor. The implications of this concept for patient care and prevention of sudden death are a challenge for future research.

Adult↗

The need for a new medical model: a challenge for biomedicine.

The dominant model of disease today is biomedical, and it leaves no room within tis framework for the social, psychological, and behavioral dimensions of illness. A biopsychosocial model is proposed that provides a blueprint for research, a framework for teaching, and a design for action in the real world of health care.

Disease↗

Stable antibiotic sensitivity disks.

Two methods of preparing sensitivity disks were compared for their effect on disk stability at 25 and 37 C. One method consisted of applying a solution of the antibiotic to blank disks by the conventional procedure; the second method consisted of applying the antibiotic to the disks as a suspension of crystals. Of the four beta-lactam antibiotics that were studied, disks made with suspended crystals were substantially more stable than corresponding disks made by the conventional method. The increased stability is related to the greater chemical stability of the antibiotics in the crystalline versus the amorphous state.

Anti-Bacterial Agents↗

[Grief and grieving].

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Adaptation, Psychological↗