Biomedical subjects

G L Ellis

Publications and source records attributed to G L Ellis.

At least 73 records · Page 4Linked to original sources

PubMed1983

Acinic cell adenocarcinoma. A clinicopathologic analysis of 294 cases.

Two hundred and ninety-four cases of acinic cell adenocarcinoma were reviewed for the purpose of defining the clinical parameters and determining the distribution of the four histomorphologic tissue patterns and five cell types for correlation to biologic behavior. The vast majority occurred in the parotid gland. There was a male predominance and a peak incidence in the third decade of life. The tumors were usually less than 3 cm in diameter and were slow growing. Pain was a common symptom, but was not indicative of prognosis. Nearly one half of the neoplasms exhibited multiple tissue growth patterns, and three fourths of the tumors displayed more than one cell type. The microcystic pattern was seen most frequently, regardless of the biological behavior of the tumors. The well-differentiated acinic cell was the most prevalent cell type except in cases with metastases, where the intercalated-duct cell type was slightly more frequent. Follow-up of 244 cases revealed a recurrence rate of 12%, a metastatic rate of 7.8%, and death rate of 6.1%. Since all histomorphologic patterns and cell types were manifest in tumors which recurred, metastasized, or caused the death of the patients, it seems appropriate to consider these neoplasms as low-grade adenocarcinomas rather than essentially benign with occasional unpredictable malignant behavior.

Adolescent↗

PubMed1983

Differentiating keratoacanthoma from squamous cell carcinoma of the lower lip: an analysis of intraepithelial elastic fibers and intracytoplasmic glycogen.

Differentiation of keratoacanthoma from squamous cell carcinoma on the vermilion mucosa of the lower lip can sometimes be difficult. Two histopathologic features that are helpful in distinguishing between these two lesions when they occur on sun-exposed skin are the incidence of intraepithelial elastic fibers and the epithelial intracytoplasmic glycogen content. An analysis of thirty-one keratoacanthomas and twenty-eight squamous cell carcinomas from the vermillion mucosa of the lower lip indicates that while the incidence of intraepithelial elastic fibers and the tumor intracytoplasmic glycogen content are greater in keratoacanthomas, these features are not reliable for differentiating between the two lesions in this location.

Carcinoma, Squamous Cell↗

PubMed1983

Ewing's sarcoma of the jaws.

Ewing's sarcoma is an intraosseous malignant tumor of questionable pathogenesis which occurs only occasionally in the jaws. Seventeen cases, eight maxillary and nine mandibular, from the files of the Armed Forces Institute of Pathology (AFIP) are reported. This neoplasm primarily affects children and young adults. Swelling and pain are frequent symptoms. Radiographically, it is most often seen as a destructive, expansile, mottled radiolucent lesion, which may produce a laminated periosteal reaction. The prognosis is poor, although some reports of combined surgery, radiation, and chemotherapy protocols have offered encouragement for increased survival. Histopathologically, Ewing's sarcoma must be differentiated from other small, round-cell malignant neoplasms, such as neuroblastoma and reticulum cell sarcoma.

Adolescent↗

PubMed1982

Squamous odontogenic tumor. Report of five cases and review of the literature.

Five previously unreported cases of squamous odontogenic tumor are reported and the literature is reviewed. This lesion appears to be a benign odontogenic neoplasm arising from rests of Malassez; it occurs over a wide range and has a predilection for the anterior maxilla and the posterior mandible. Maxillary lesions are more aggressive than mandibular ones. The most common sign is mobility of teeth in the area. Radiographically, the most characteristic picture is that of a well-circumscribed semicircular radiolucency bounded by a sclerotic border and emanating from the area of the alveolus adjacent to the roots of teeth. The histologic features are sufficiently characteristic to differentiate it from ameloblastoma and epidermoid carcinoma; however, evaluation of the entire clinicopathologic picture is necessary to exclude the diagnosis of squamous odontogenic tumorlike proliferations in an odontogenic cyst.

Adolescent↗

PubMed1981

Adenomatoid hyperplasia of mucous salivary glands.

Ten cases of an intraoral salivary gland lesion that is rarely reported and described. Clinically, these lesions appear as asymptomatic tumorlike nodules which are characterized histologically by a proliferation of mucous glandular tissue. The palate was the site of nine lesions. This entity may represent either a reactive hyperplastic phenomenon or a hamartomatous proliferation and should be distinguished from neoplasm.

Adenoma↗

PubMed1980

Intraosseous lymphangiomas of the mandible.

Central lymphangioma of bone is a rare entity which has not previously been reported in the English language literature as occurring in the mandible. Two cases of intraosseous lymphangioma of the mandible from the files of the Armed Forces Institute of Pathology are presented. While these lesions have clinical and radiographic features similar to hemangioma of bone, they do not pose the surgical hemorrhage control problems of hemangiomas. Solitary lymphangioma of bone may share similar histologic features with the disease entities systemic cystic angiomatosis and massive osteolysis. These latter two entities may cause complicated clinical management problems; curettage, however, is adequate therapy for solitary, localized lymphangioma of bone.

Adult↗

PubMed1980

Spindle cell carcinoma of the oral cavity. A clinicopathologic assessment of fifty-nine cases.

The clinical features, histomorphologic characteristics, therapeutic results, and follow-up data for fifty-nine cases of spindle cell carcinoma of the oral cavity were analyzed. Circumstantial evidence favors a pathogenesis from metaplastic malignant epithelial cells for the spindle cell proliferation. These neoplasms occurred most frequently on the lower lip, tongue, and alveolar ridge in either polypoid, exophytic, or endophytic configurations. A male predominance was attributed to a military and veteran bias. Mean age at occurrence was 51 years for men and 67 years for women. Symptoms were infrequently reported. Histomorphologically, fasciculated, myxomatous, and streaming patterns of the spindle cells were observed, with variable mitotic activity, pleomorphism, benign and atypical giant cells, inflammation, vascularity, and infiltration. Follow-up data on forty-five patients revealed that only fourteen were alive and well, whereas twenty-five were dead of their disease. Mean survival time for those dead of the disease was under 2 years. Five-year survival was a significant indicator of cure. No clinical or histomorphologic characteristic other than distant metastasis was found to be a reliable prognostic indicator. Wide surgical excision, alone or with radical neck dissection, was the most successful therapeutic modality. Radiation was ineffective.

Adult↗

PubMed1980

A social worker's use of a patient attitude survey in the administration of a small health clinic.

This paper has been a report of a patient attitude survey with 100 randomly selected parents and/or adult patients. It demonstrates that most consumers of our service were pleased with the humaneness and competence of the professional staff. It identified areas of weakness which needed improvement. Constructive action to correct these weaknesses has been initiated. Therefore, this process has demonstrated the value of client feedback for agency operation. It is important to caution the reader that because of the vulnerability of the patients they learn to be accommodating even if unintentional agency practices embarrass and degrade them. The value of patient satisfaction as a measure of the humanism provided by an agency depends on the population being served--their expectations, fears, and hierarchy of concerns.

Adult↗

PubMed1979

Focal myositis of the perioral musculature.

Focal myositis, a benign inflammatory pseudotumor, is a relatively newly defined clinicopathologic entity which arises as a rapidly enlarging swelling within an isolated skeletal muscle. It occurs most often in the lower extremity, and we are reporting what we believe to be the first cases of perioral involvement. There is no apparent age or sex preference. Focal myositis must be differentiated from neoplasm, nodular pseudosarcomatous fascilitis, proliferative myositis, myositis ossificans, polymyositis, and, in the oral region, salivary gland lesions and hypertrophic branchial myopathy. No lesions have recurred.

Adult↗

PubMed1977

Malignant neoplasms metastatic to gingivae.

Malignant neoplasms metastatic to the gingivae are rare. Our review of the literature revealed only eight acceptable examples. We are reporting two additional cases. One patient was a 58-year-old man with an adenocarcinoma of the lung which metastasized bilaterally to the maxillary gingiva. The second patient was a 27-year-old man with a synovial sarcoma which metastasized to multiple sites in the maxillary and mandibular gingiva. Clinically, gingival metastatic lesions are most often confused with hemangioma, pyogenic granuloma, giant-cell granuloma, and pepripheral fibroma. They usually occur late in the course of the disease and are associated with metastatic deposits in many other organs and tissues. Death usually occurs in a few weeks or months after discovery of the gingival metastasis.

Adenocarcinoma↗

PubMed1977

Intraosseous benign neural sheath neoplasms of the jaws. Report of seven new cases and review of the literature.

Benign neural sheath neoplasms occurring centrally within the jaws are most uncommon. Our search of the English-language literature revealed twenty-eight previously reported cases. Seven additional cases--five neurofibromas and two neurilemmomas--are newly described here. Most cases have not been associated with multiple neurofibromatosis. These tumors occur predominantly in females, in patients under 45 years of age, and in the posterior mandible. The tumors generally present as asymptomatic radiolucencies, but some are associated with pain and/or swelling. Neurofibromas tend to recur more often than neurilemmomas when treated by conservative local excision.

Adult↗

PubMed1976

PSRO: current status of the professional standards review organization program.

Since Public Law 92-603 was enacted in October 1972 considerable progress has been made in the establishment of Professional Standards Review Organizations (PSROs) for the purpose of determining the necessity, appropriateness, and quality of medical care provided beneficiaries of the major programs authorized in the Social Security Act. Sixty-five conditional PSROs are implementing review in acute care hospitals in their geographic area, and 55 planning groups are developing plans to qualify for conditional PSRO designation. The PSRO hospital review system is based on three interrelated review mechanisms. These are concurrent review, which includes admission certification, and continued stay review through discharge; medical care evaluation studies; and analysis of hospital, practitioner, and patient profiles. This article describes the review system in some detail and the potential opportunities the PSRO program offers to occupational therapists.

Hospitals↗

PubMed1975