[Evaluation of the effectiveness of preventing premature labor by intravenous infusions of ethanol].
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Biomedical subjects
Publications and source records attributed to G Krasomski.
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The purpose of this study was to examine the intraerythrocytic 2,3-diphosphoglycerate (2,3-DPG) concentration in anaemic (haemoglobin concentration below 10.5 g/100 ml blood) and in normal pregnant women (haemoglobin concentration above 12.5 g/100 ml blood). The authors showed that the 2,3-DPG concentration increased systematically between the 16th and 42nd weeks of pregnancy, both in the control group and in pregnant women with anaemia. However, in the group of anaemic pregnant women the 2,3-DPG concentration was higher in each stage of pregnancy.
We have found a high negative correlation between the 2,3-DPG level and the duration of labour (r = -0.586). The correlation between red cell 2,3-DPG concentration and newborn birth weight was 0.576. Both relations are statistically significant with p less than 0.01. These results suggest that the increased 2,3-DPG concentration in maternal red cells facilitates the release of oxygen to uterine muscle and to the foetus and thus helps the normal intrauterine development of foetus and reduces the duration of labour.
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