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Biomedical subjects

G Kraatz

Publications and source records attributed to G Kraatz.

At least 37 records · Page 2Linked to original sources
PubMed1989

[HLA antigen frequencies in patients with autosomal dominant polycystic kidney degeneration].

20 non-related patients suffering from autosomal dominantly polycystic renal disease were HLA-A, -B, -C and -DR typified and the HLA frequencies were compared with the normal population. Tissue typing was performed using the lymphocytotoxicity test using 180 well-characterized test sera. In contrast to the literature no significant differences were found. However, the value of erythrocytic phosphoglycolate-phosphatase-phenotyping should be checked in the genetic control and consultation.

Chromosome Aberrations↗
PubMed1988

[Preventive use of nitrofurantoin in recurrent urinary tract infections].

51 patients suffering from chronic urinary tract infection were treated from 6 to 12 months with a single evening dose of 100 mg nitrofurantoin. The frequency of re-infection in the treatment period was compared with the same period before onset of therapy. The number of such re-infections was reduced significantly. Side effects of this therapy were substantial lower than after a three-times application per day. Gastrointestinal symptoms could be reduced in more than 50% of the cases by a combined therapy of 100 mg nitrofurantoin and 20 mg vitamin B6.

Adolescent↗
PubMed1985

Tubular dysfunctions in the diagnostic differentiation of glomerulonephritis, pyelonephritis, and diabetic nephropathy.

Concentration and acidification capability was tested in 41 patients with chronic pyelonephritis (PN), 14 patients with chronic glomerulonephritis (GN), 16 patients with diabetic nephropathy (DNP) and 12 healthy controls. Significant differences appeared between PN and GN, PN and DNP comparing a quotient between percent of normal osmolarity and percent of normal creatinine clearance. Similar results were obtained using a quotient creatinine clearance/ammonia excretion, which enabled the differentiation of PN from the other groups. The tubular functions of concentration and ammonia excretion in relation to creatinine are clinically useful in the differentiation of pyelonephritis from glomerular kidney diseases.

Ammonia↗
PubMed1984

[Measurement of activated whole blood coagulation as a control parameter for heparin dosage in hemodialysis].

A precise dosage of heparin is necessary especially in acute dialysis, but also in chronic dialysis. This can be checked by measuring the partial thromboplastin time, the thrombin time, the coagulation time according to Lee-White or, recently, by automatic measurement of activated whole-blood coagulation. For the latter only 0.5 ml of whole blood is necessary. In a total of 44 examinations the activated whole-blood coagulation time was shown to be well reproducible. In the 40 patients examined there was considerable variation in the sensitivity to and the elimination rate of heparin, which indicates the necessity of individual heparin dosage. Measuring the activated whole-blood coagulation time proved to be suitable for classifying the patients.

Blood Coagulation Tests↗
PubMed1983

[Results of sonographic kidney diagnosis].

In a prospective study of the examination of the accuracy of the ultrasound tomography in the renal diagnostics the kidneys of 361 patients could be demonstrated as at 100% sufficiently to be judged. Tumours, congestion kidneys, cystic kidneys/renal cysts and cirrhoses of the kidney were diagnosed with an efficiency of 0.92-0.96-0.97-1.0. The sensitivity was in the same order 0.90-0.96-0.99-1.0 and the specificity 0.94-1.0-0.95-1.0. Insufficient results were obtained by the sonographic search for renal calculi. As non-invasive and rapid method of diagnostics the sonography in a valuable way contributes to the differentiation of the symptom "quiescent kidney" and oligo-anuria.

Humans↗
PubMed1979

[Pseudo-lupus erythematosus syndrome and interstitial nephritis].

First in 1972 under the preliminary term pseudo-lupus-erythematodes-syndrome a clinical picture was represented which clinically resembles the lupus erythematodes disseminatus and which is characterized by the proof of antimitochondrial antibodies and the lack of antinuclear factors. We report on a female patient with this syndrome and interstitial concomitant nephritis. Possible causal factors, clinical picture, typical laboratory findings, therapy and prognosis are discussed with the help of the casuistics.

Adult↗
PubMed1978

[Simultaneous diagnostic studies of bacteriuria as related to method of urine collection].

In a direct comparative series were compared 204 functional, catheter, and mid-stream urines which were got simultaneously in patients with chronic pyelonephritis. In suprapubic vesical puncture 113 had a sterile urine, 91 showed a bacteriuria. After catheterisation 103 specimens were still sterile and 101 were bacterially infected. Of the mid-stream urines only 90 proved sterile, and 114 times pathogenic agents could be proved. While in males mid-stream urines achieved good results, in females a contamination was pretty frequent. Repeated investigations, estimation of the number of germs, and optimum taking essentially improve evidence. Though in females by means of catheterisation better bacteriological results may be achieved, in rare cases there is the danger of the invasion of germs. A clear judgment is possible, using the suprapubic vesical puncture.

Bacteria↗
PubMed1977

[Relationships between the value of combined PAH-inulin clearance, the kidney-cortex index as well as between additional radiographic findings in chronic pyelonephritis].

In 85 patients with ascertained chronic pyelonephritis the relations between the measured values of the combined PAH-inulin-clearance, the index of the adrenal cortex and other radiological findings were investigated. Here the determination of the cortex of the adrenal cortex resulted in a better correlation with the sizes clarification values than the calculation of the size of the kidney. By variance analysis (F-test) significant differences between the individual function groups became clear.

Aminohippuric Acids↗
PubMed1977

[Incidence and therapy of fungal infections of the efferent urinary pathways].

Manifest infections with fungi of the urinary tract are rare in comparison with bacterial diseases and therefore they are often overseen. When this is concerned a funguria must always be clarified in chronic pyelonephritis. In patients with manifest infections with fungi without pronounced renal insufficiency 5-fluorocytosin is therapeutically very well suited on account of the renal elimination.

Aged↗
PubMed1977

[Distinct hypokalemia in leukotic infiltrates of the kidney].

Report on a 74-year-old female patient falling ill from a chronic myelosis. Due to leukotic infiltrates of the kidneys renal loss of potassium and extreme hypopotassaemia appeared. On the basis of the present literature clinical symptomatology and morphological finding are discussed.

Acid-Base Equilibrium↗
PubMed1975

[Serum creatinine and endogenous creatinine clearance].

It is reported on the clinical evidence of the determination of creatinine and of the endogenic creatinine clearance. The determination of the serum creatinine gives a good parameter for the observation of the course in advanced renal insufficiency. The endogenic creatinine clearance which is often carried out in the clinical practice in the normal and moderately limited region allows in most cases sufficient measurement of the filtrate of the glomerulum. On 118 in-patients a method was tested which allows a nomographic estimation of the endogenic creatinine clearance on the basis of the actual serum creatinine level, taking into consideration age, sex, and bodyweight.

Age Factors↗
PubMed1975

[Measurement of kidney function using combined PAH-inulin clearance before and after bactericide treatment of chronic pyelonephritis].

On account of the solution of the problem, whether already after a four weeks' therapy with antibiotics in chronic progressing pyelonephritis a measurable increase of function may develop, the combined PAH-inulin-clearance was performed 35 times. 9 patients did not show a clear restriction of the clearance, wherefore in these cases a control examination was not necessary. In 10 patients of 12 an increase was present, in 7 patients a significant increase of the renal function existed after the therapy carried out. Therefore already after antibiotic impact therapy in patients with chronic pyelonephritis without provable acute episode an improvement of the function can occur, which is to be increased or kept by means of the long-term treatment.

Aminohippuric Acids↗