Search PubMed⌕ Search

Biomedical subjects

G Kostov

Publications and source records attributed to G Kostov.

23 records · Page 2Linked to original sources
PubMed1977

[Differentiation of non-specific positive brucellosis reactions using an antigen stained with rose bengal].

A Brucella buffered antigen, stained with Bengal rose by a method of the authors, was obtained. It showed a high distinguishing capacity with regard to the nonspecific agglutinations after Huddleson and Wright at a negative complement-fixation test for brucellosis with sera from cattle, pigs, sheep, and horses. Such differentiation, however, proved to be incomplete and for sera of different animals varied within the range of 34 to 0.0 per cent.

Agglutination Tests↗
PubMed1977

[Transmission of a delayed allergic reaction to Salmonella abortus-ovis via the blood plasma of gamma-irradiated guinea pigs].

Use was made of blood plasma taken from guinea pigs (sensibilized with a live culture of Salmonella abortus ovis and then irradiated wiht 800 rad gamma-rays) to transmit the skin allergy reaction to normal, nonsensibilized guinea pigs. The allergy reaction was demonstrated in the recipients of plasma as early as the 3-4th hour following the injection of the allergen into the skin. It reached its peak at the 12-24th hour and later on strongly diminished, remaining in few of the animals only up to the 48th hour. The infiltrate at the site of injection in the skin of positively reacting animals contained at the 24th hour cells of the polymorphonuclear type which predominated, while the cells of the mononuclear type were few in number. There were no precipitins in the plasma of the donors, and the titer of the agglutinins and the cytophile antibodies was very low. Regardless of these findings it was concluded that the transmitted allergy reaction was of the fast type (after Arthuss), and not of the delayed one.

Agglutinins↗
PubMed1977

[Induction of an allergic response of the delayed type against Salmonella abortus-ovis].

Studied were several of the conditions of inducing an allergy reaction of a delayed type in guinea pigs experimentally infected with Salmonella abortusovis as well as the correlation between the production of agglutinins and precipitins and the allergic reaction of a delayed type. It was found that a live culture of Salmonella abortusovis produced strongest allergic effects when injected into the pads. The injection (in the pads) of a killed culture, using no adjuvant, and the oral administration of a live culture did not sensibilize the animals. No correlation was established between the agglutinin and precipitin production and the allergic reaction of a delayed type.

Agglutinins↗
PubMed1975

[Some properties of cytophil antibodies against the O-antigen of Salmonella abortusovis].

Boyden's multilayer method was made use of to study the resistance to mercaptoetanol, and to temperature effects as well as the fixation capacity of macrophages of other animal species as regards cytophil antibodies from sera of guinea pigs immunized with a live culture of Salmonella abortusovis. It was found that they are resistant to heating at 56 degrees C for 30 minutes, to mercaptoetanol, and are not fixed by murine macrophages. Discussed is the biologic value of such type of antibodies.

Animals↗