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G Kellner

Publications and source records attributed to G Kellner.

80 records · Page 5Linked to original sources
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[Cytology and histochemistry of synovial cells in various forms of arthritis].

Synovial effusions from various kinds of arthritis have been examined both morphologically and histochemically. These two methods give complementary evidence, and show (i) that there are two fundamentally different types of cell present in rheumatoid arthritis (ii) that the synovial fluid from septic arthritis can clearly be separated from that of all other forms of arthritis and (iii) that intracellular crystals can be demonstrated in gout. Laboratory methods also give information on the polysaccharide and fat content of synovial fluid, in particular on the lipid material in the cell free supernatant. Large mononuclears in the fluid are probably generated in the local tissue and reflect minimal differentiation from a basic cell type.

Arthritis↗
PubMedDate not supplied

[Local and systemic parameters in the synovial milieu].

Our own results as well as recent data from the literature confirm the already long known fact, that synovial fluid analysis allows only in very few diseases as for example a crystal synovitis a definite diagnosis in the individual case. In the majority of the patients this technique permits only to differentiate between inflammatory and non-inflammatory joint disease as well as an estimation of the local inflammatory activity of joint. The simultaneous histologic examination of synovial membrane according to our experience seems to bring no major additional information which exceeds the information given by each technique alone.

Acid Phosphatase↗
PubMedDate not supplied

[Guidelines for synovial cytology].

Certain technical requirements have to be satisfied when synovial fluid is submitted for evaluation. This is to enable examination of the cell morphology and the polysaccharide and lipoid histochemistry of the cells and the dried liquid phase. The cell physiology should be considered when evaluating the cytogramme. Morphological and histochemical examination of the background indicate which biochemical estimations of the liquid phase are needed, and thus represent added diagnostic tools for evaluation of joint diseases. Cytolysis, cell involution and substrate condensation are discussed in detail.

Arthritis↗