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Biomedical subjects

G Kantor

Publications and source records attributed to G Kantor.

79 records · Page 5Linked to original sources

[An anthropological study of radiotherapy care experience].

An anthropological study has been carried out in order to evaluate the need expressed by patients undergoing radiotherapy treatment. The study was mostly qualitative and based on the radiotherapy experiences of 13 women with breast cancer and six men with head and neck cancer. A 24-year-old female anthropologist spent one year in the department of radiotherapy at the Bergonié Institute in Bordeaux. She collected data on patients' needs through the observation of their experience of treatment and personal interviews. These were put in context, analyzed both by qualitative and quantitative methods. The results point out the need for more information on the different steps of treatment and the patient's need 'for a smile' from the medical team; in other words, emphatic support.

Adult↗

[Radiosurgery of single brain metastasis without combined total cerebral irradiation. Results of a consecutive series of 12 cases].

PURPOSE: To evaluate the usefulness of radiosurgery without whole brain irradiation for a solitary brain metastasis. PATIENTS AND METHODS: Between December 1994 and November 1996, 12 patients were treated for a single brain metastasis by radiosurgery alone. Median age was 53, and 10 patients had a Karnofsky performance status above 70. Half the patients had active extracranial disease at the time of radiosurgery. Stereotactic radiosurgery delivered a single dose of 20 Gy (specified at the isocenter with a 70% isodose reference curve). Evaluation of results was performed according to local control, survival, evolution of performance status, as well as evolution of neurologic symptoms. RESULTS: No patient had immediate toxicity. One month later, ten patients showed improvement in their neurologic impairments, and none had progression of the cerebral lesion according to CT scan evaluation (diminution for seven patients, and stabilization for five). Local control rate was 58%, and median time to failure was 4 months. The overall median survival time was 10 months. Three patients were alive, with good performance status, and six died following cerebral progression. CONCLUSION: These poor results in terms of local control are in favor of supplementary whole brain irradiation, except for particular cases.

Adenocarcinoma↗

[Radiosurgical activity in France. Surveys of the French Society of Oncologic Radiotherapy (SFRO)].

The total record of 3,407 radiosurgical treatments performed from 1986 to 1996 is described per center and per diagnosis. Treatment of arteriovenous malformation (AVM) remains the principal indication (approximately 40%) before treatment of metastasis (approximately 20%). Annual incidence of radiosurgery for AVM can be estimated to 5 per million inhabitants per year in France. First therapeutic results of AVM series are described.

France↗

[Radiotherapy in stereotactic conditions (radiosurgery) in malignant brain tumors: clinical research].

We have looked for trials which are in progress in the field of stereotactic radiotherapy (radiosurgery) of malignant brain tumors. Most randomized trials are conducted by the Radiation Therapy Oncology Group (RTOG) or the European Organization for Research and Treatment of Cancer (EORTC) and assess the role of radiosurgery in treatment of high grade glioma and brain metastasis.

Brain Neoplasms↗

[Postoperative radiotherapy of a benign tumor of the ankle].

Pigmented villonodular synovitis is a rare benign tumor. The high rate or recurrence after surgery exposes the risk of non-conservative or non-functional treatment. External irradiation of post-surgical residual disease seems to be useful for the prevention of relapse and conservation with a good functional result. We report a clinical observation of a case with a diffuse type of pigmented villonodular synovitis of the ankle, operated on three times, and then treated by external irradiation. The published results in terms of response and functional prognosis of 14 cases of multi-recurrent villonodular synovitis treated by irradiation seem to confirm this therapeutic option.

Ankle↗

CDRH RF phantom for hyperthermia systems evaluations.

The National Cancer Institute (NCI) sponsored clinical evaluations of investigational 'regional' hyperthermia systems at four clinical institutions. To support this project, the Center for Devices and Radiological Health (CDRH) developed a series of test instruments to evaluate the magnitude and repeatability of the induced heating by radiofrequency (RF) systems. Data from three institutions using the same model hyperthermia system have been analyzed. After heating, the average temperature from measurements taken at several points in the test phantom at each institution agree within +/- 0.002 degrees C. These differences are about equal to the measurement uncertainty. Thus, this technique can be used for preclinical evaluation and quality control of the total system operation. After one of the institutions relocated its hyperthermia system, a subsequent set of data showed inconsistencies compared to their earlier data. Investigation traced this to cable loss and power meter interference. From the analysis of the data from the three institutions, the utility of the CDRH RF phantom for hyperthermia systems evaluation is demonstrated.

Equipment Design↗