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Biomedical subjects

G Kamen

Publications and source records attributed to G Kamen.

45 records · Page 3Linked to original sources
PubMed1980

Regional adipose cellularity and reliability of adipose cell size determination.

Regional adipose cell size was assessed in 18 males ranging in age from 20 to 36 years. These measures were correlated to total body fat determined by hydrostatic weighing. Adipose samples were removed from the gluteal, abdominal, and subscapular regions using a needle aspiration technique. The tissue was incubated in collagenase to release individual cells that were immediately photographed under a microscope. To establish the reliability of adipose cell size assessment over time, fat biopsies were secured on 2 separate days. No significant difference was found for any region between day 1 and 2 adipose cell measures. Gluteal cell diameter (90.3 mu) was significantly larger than the abdominal (81.0 mu) and subscapular (78.6 mu) cell diameter (90.3 mu) was significantly larger than the abdominal (81.0 mu) and subscapular (78.6 mu) cell diameters. Total body fat correlated highest with gluteal cell size (r = 0.76) compared with the abdominal (r = 0.67) or subscapular (r = 0.70) regions. This study also examined the number of adipose cells required to subscapular (r = 0.70) regions. This study also examined the number of adipose cells required to obtain a reliable and representative mean value of adipose cell size. Using a sequential estimation analysis it was found that adipose cell diameters of the abdominal, gluteal, or subscapular regions can be reliably estimated with fewer than 100 cells.

Abdomen↗
PubMed1980

Post vibratory effects on fractionated reaction time and maximum isometric strength.

Knee and ankle extension isometric strength and reaction time under resisted and unresisted conditions were examined before and after 100 seconds of vibration. Subjects included 10 low strength distance runners and 9 high strength power athletes. The reaction time measures were fractionated into premotor time, corresponding to nervous system processing time, and motor time, corresponding to muscle contraction time. Vibration resulted in no significant change in ankle or knee extension strength or in any ankle extension reaction time component. For knee extension, however, a significant lengthening in unresisted motor was found after vibration. Initial strength level of the subjects was not a factor since the two groups responded to vibration in the same manner for all criterion measures. The results of the present study do not support the use of the post vibratory period for therapeutic purposes.

Adult↗
PubMed1979

Serial isometric contractions under imposed myotatic stretch conditions in high-strength and low-strength men.

The immediate effects of an imposed myotatic stretch on knee extensor force were studied in 12 high-strength and 12 low-strength men. Under nonfatigued pre-exercise conditions, significant tension increases of 6.5% for the high-strength group and 11.0% for low-strength subjects were observed as a result of the imposed stretch. An exercise treatment involving 28 serial isometic contractions, each of 5 s duration, with an intertrial rest period of 10 s was administered. This fatiguing exercise resulted in significant decrements in strength on the order of 28.0% and 18.5% for the high-strength and low-strength groups, respectively. A Similar treatment which included a 1 s imposed myotatic stretch during each trial resulted in a greater strength decrement for the low-strength group (26.4%) than for the high-strength subjects (15.0%). A neural factor involving the stretch reflex is tentatively suggested as a plausible explanation accounting for the observation that high-strength subjects fatigue faster than low-strength subjects under conditions of isometric exercise, while low-strength subjects fatigue faster than high-strength individuals in isometric exercise which is performed with an imposed stretch.

Adult↗
PubMedDate not supplied

Contralateral influences on patellar tendon reflexes in young and old adults.

In an effort to more fully investigate age-related changes in spinal reflex parameters, we measured force-time characteristics of the patellar tendon reflex in aged subjects and contrasted these with data obtained from college-age individuals. We also conditioned the tendon jerk with a tap to the contralateral tendon. The results showed a marked tendon reflex enhancement in the old group, consisting of greater overall reflex force produced by the quadriceps. In both groups, the contralateral conditioning stimulus produced a short-latency inhibition (at 25 msec) followed by a longer-latency facilitation (beginning at 75 msec). Both the early inhibition and the later reflex enhancement were greater in the aged subjects. We suggest that some age-related change may occur at the spinal level to compensate for decrements in more complex motor functioning.

Achilles Tendon↗
PubMedDate not supplied

Firing rate interactions among human orbicularis oris motor units.

Groups of human motor units from the same muscle exhibit joint fluctuations in firing rate during voluntary muscle contraction. In an effort to determine whether similar behavior would be observed in a muscle lacking muscle spindles, motor unit firing behavior was examined in the human orbicularis oris inferior (OOI) during mild voluntary effort. Motor unit activity was recorded with a quadrifilar needle inserted in the OOI. Firing occurrences were identified using a motor unit decomposition procedure. Cross-correlation of motor unit firing rates revealed a tendency for motor unit firing rates to covary, although the effect was somewhat more variable than that observed previously in other skeletal muscles. There was also a statistically significant tendency for pairs of motor units to fire at simultaneous or near-simultaneous (+/- 5 ms) intervals (synchronization). Firing rate variability in OOI motor units was not significantly different (p > .05) from that observed in the FDI. Thus, the present results suggest that the common drive of human motor unit activity may not depend on the presence of muscle spindles.

Action Potentials↗