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Biomedical subjects

G Kallistratos

Publications and source records attributed to G Kallistratos.

At least 37 records · Page 2Linked to original sources
PubMed1975

Treatment of cystinuria with Thiola (alpha-mercaptopropionyl glycine).

Nine cystinuric patients (8 females and 1 male) with recurrent L-cystine stone formation have been treated since 1971 with the new drug Thiola (alpha-mercaptopropionyl glycine). Thiola was found to be more effective than D-penicillamine in dissolving L-cystine. In two case a partial dissolution was observed after 20 months of Thiola administration. In four cases further stone growth was stopped. In the last two cases stone growth occurred even after administration of Thiola. Tolerance of the drug was good, and no serious effects were observed sufficient to interrupt treatment.

Amino Acids, Sulfur↗
PubMed1975

Litholytic agents with bacteriostatic properties in conservative treatment of urolithiasis.

Litholytico-bacteriostatic agents such as ethylenediaminetetraacetic acid (EDTA) can be used for direct dissolution of calcium and magnesium containing urinary stones. By means of a double-channel catheter (Timmermann) and the corresponding technique a direct irrigation of the kidney cavities with EDTA solutions was possible, without any serious side effects (instrumental stone chemolysis method). It must be pointed out that the instrumental chemolysis can be clinically applied only by a specialised scientific staff, and improvisation may cause serious complications; further development of new potential litholytico-bacteriostatic agents is necessary in order to increase effectiveness of the method. Some clinical results are reported concerning the indications for this method by X-ray illustrations of successfully treated cases.

Administration, Oral↗