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Biomedical subjects

G Kalifa

Publications and source records attributed to G Kalifa.

At least 73 records · Page 4Linked to original sources
PubMed1994

[Responses of medical imaging in battered children. The Silverman-Ambroise Tardieu syndrome].

Imaging procedures offer an important contribution to the syndrome of the abused child that F.N. Silverman himself proposes to call the Ambroise Tardieu syndrome. First they disclose and analyse the lesions which may involve bones, encephalon or spinal cord, viscera, soft tissues. Then they must answer four questions: Traumatic lesion or normal variant? If traumatic, are there arguments pointing to abuse, for instance multiple bone lesions of different ages and more specifically fractures of ribs, clavicle, spine, pelvis, phalanxes? Is there a possibility of a general disease explaining such traumatic lesions? Etiologies are revised including sensibility deficits. Finally are the bad treatments inflicted with an intention of hurting, injuring or destroying? The answer results of a discussion with clinicians and social interveners but some lesions, as phalanx fractures, may be determining. In this situation that involves the vital prognosis and may induce severe sequellae the imaging strategy, fully described, is of paramount importance.

Battered Child Syndrome↗
PubMed1993

Direct Ethibloc injection in benign bone cysts: preliminary report on four patients.

Benign bone cysts often require treatment in order to prevent pathological fracture. We report preliminary experience with percutaneous injection of Ethibloc in four children (8-15 years old) presenting with benign bone cysts: two were aneurysmal bone cysts, two were unicameral bone cysts. All the patients were followed up for 12-18 months. Healing was satisfactory in all cases and no complications occurred.

Adolescent↗
PubMed1993

Fibrodysplasia ossificans progressiva and synovial chondromatosis.

Two cases of an unusual association-fibrodysplasia ossificans progressiva and synovial chondromatosis-in non-related children are presented. This association does not seem coincidental and raises several questions about the pathogenesis. A genetic hypothesis related to G proteins is proposed. This is supported by the fact that such abnormalities have been demonstrated in pseudohypoparathyroidism and fibrous dysplasia; these diseases can also be associated with fibrodysplasia ossificans progressiva.

Adolescent↗
PubMed1993

Radiological findings in three cases of persistent müllerian duct syndrome.

We report three cases of persistent Müllerian duct syndrome, which is a rare form of inherited male pseudohermaphroditism characterized by the presence of a uterus and tubes in otherwise normally virilized 46,XY males. We emphasize the usefulness of ultrasonographic study of the pelvis and inguinal areas in the preoperative diagnosis, which is difficult. We recommend that ultrasound be performed routinely in bilaterally cryptorchid patients.

Adolescent↗
PubMed1993

[Ultrasonography of the hip in infants].

Ultrasonography of the hip in high risk newborns is the natural extension of clinical examination to the diagnosis of congenital dislocation and dysplasia of the hip. At the end of the first month, ultrasonography allows a better adjustment of therapeutic to the orthopaedic status.

Hip Dislocation, Congenital↗
PubMed1992

Impairment of lung diffusion capacity in Schönlein-Henoch purpura.

Twenty-nine children with typical Schönlein-Henoch purpura (SHP) were tested at the initial phase of the disease for respiratory function. Of the 29 patients, 28 had a decrease of lung transfer for carbon monoxide (TLCO) as measured by a steady-state method. Lung volumes and blood gas values were normal; slight radiologic signs of interstitial lung involvement were observed in 18 of 26 patients. There was a decrease in TLCO to 56.8% of normal values for height and gender and to 58.5% when normal values were volume-adjusted to functional residual capacity. In 19 of 25 patients, TLCO measurements were performed at 3-month intervals during follow-up. In all cases, normalization of TLCO values was observed only after complete clinical recovery from SHP. All children with persisting symptoms, even limited to microscopic hematuria or slight proteinuria, had low TLCO values. In one patient low TLCO during follow-up preceded a late relapse of SHP in the form of acute nephritic disease with characteristic IgA deposits on renal biopsy. We conclude that low TLCO in SHP is probably related to alteration of the alveolar-capillary membrane by circulating immune complexes. This noninvasive technique may be useful in diagnosis, and during the follow-up of the disease as an early indicator of reactivation.

Carbon Monoxide↗
PubMed1992

Brain MRI and electrophysiologic abnormalities in preclinical and clinical adrenomyeloneuropathy.

We describe the neurophysiologic abnormalities in 17 patients with clinical adrenomyeloneuropathy (AMN), an adult phenotype of X-linked adrenoleukodystrophy (ALD). These abnormalities also allowed the early recognition of the AMN phenotype in three asymptomatic boys with biochemically proven ALD. In 14/16 adult AMN patients, there were cerebral white matter abnormalities on MRI which were severe and comparable with cerebral ALD in four of the patients.

Addison Disease↗
PubMed1992

[Imaging in pediatrics. Strategy and economic implications for the Third World].

The cost of acquiring medical imaging equipment is too high for many Third World nations. Ultrasonography and conventional roentegenography provide adequate data in most pediatric patients in tropical countries, for a low maintenance cost. Special training of practitioners in the use of these investigations is essential, before even performing the necessary choices among available equipment.

Developing Countries↗
PubMed1992

[X-ray findings in pulmonary tuberculosis in children and its complications].

Pulmonary tuberculosis is still a common disease in children, especially those of immigrant families. Prevention and diagnosis rest on the plain chest film which should remain the first step of the work-up. Apart from cerebromeningeal complication, CT scan is also useful for evaluating chest lesions including mediastinal lymphadenopathies and lung parenchyma involvement. CT scan combined with endoscopy ensures detection of complications including bronchogenic dissemination. With a few cases as illustrations, the role of roentgenographic investigations in the management of pediatric tuberculosis is outlined.

Adolescent↗
PubMed1992

[A retrospective study of preadoption x-ray findings in young children at the Social Child Aid: value and limitations].

French law requires that children awaiting adoption undergo full medical evaluation to detect anomalies which may influence decisions concerning adoption. As part of this evaluation, all infants admitted to the Saint-Vincent-de-Paul Preadoption Center in Paris undergo roentgenographic evaluation including frontal and lateral films of the skull, a frontal chest film, a frontal view of the pelvis, and frontal films of one upper limb and one lower limb. A study of the one hundred most recent evaluations, carried out in infants aged 1 to 14 months, disclosed 16 roentgenographic anomalies. Five of these anomalies were already known prior to the evaluation, 2 did not give rise to additional investigations, and 9 led to additional tests, a change of therapy or subsequent radioclinical monitoring. Among the six films taken in each patient, only the frontal views of the chest and pelvis proved informative. Screening using these two roentgenograms only is recommended, with other roentgenograms being performed if called for on the basis of clinical findings.

Adoption↗
PubMed1991

Contribution of MRI to the diagnosis of cerebral lesions of adrenoleukodystrophy.

33 cases of adrenoleukodystrophy in children have been studied. Brain MRI was performed in these patients in order to appreciate the benefits of this technic in patients presenting with the cerebral type of ALD [21]. 12 neurologically asymptomatic patients with the same biochemical disorder were studied. In both groups, MRI is the best imaging modality. In symptomatic patients lesions were clearly demonstrated with excellent clinical correlations. In addition, MRI can depict brain lesions in asymptomatic patients before devastating brain damage occurs. MRI is the essential step before proposing specific treatment to these patients.

Adolescent↗
PubMed1991

Minor tibial duplication: a new cause of congenital bowing of the tibia.

Five infants presented with a congenital anterolateral, unilateral bowing of the tibia. The fibula was normal but a bifid homolateral great toe was seen, associated with hand malformations. Plain films and CT disclosed a short tibial duplication, with distinct corticals. We do think that this abnormality represents a new entity, and may be related to a genetic anomaly. The long term follow up of our patients shows a spontaneously favourable prognosis without any association with pseudarthrosis. The only therapeutic problem is a limb length discrepancy.

Abnormalities, Multiple↗
PubMed1989

Value of systematic post mortem radiographic examinations of fetuses--400 cases.

A retrospective study of 400 cases of fetal deaths has been carried out to assess the value of systematic post mortem radiological examination. Apart from general diagnosis purpose, special attention was given to the assessment of bone age and mineralization. The results were correlated with the clinical, U.S., chromosomal and pathological data. Computerized analysis of our information show the following results: (1) The radiological examination was valuable for the final diagnosis in 13.5% of cases. (2) It brings additional information in 34.5% of cases. (3) It had no diagnostic value in 52%. Furthermore, several points deserve attention such as apparition of teeth (21 weeks), calcaneum (24 weeks). Major osteoporosis was always associated with a constitutional bone disease or an infectious process. An excessive length of the upper limbs (12) was seen in 11 cases of anencephaly. We suggest that a radiological examination should not be routinely performed, when the diagnosis is otherwise obvious, but should be considered in the presence of dwarfism, or other limb abnormalities and when the gestational age is uncertain. The films provide essential information especially for further genetic counselling. Systematic post mortem radiographic examinations are performed in all naturally aborted fetuses over 11 weeks of gestation in our institution. A retrospective study of the last 400 cases was designed in order to assess the value of this examination, with regard to overall diagnosis and assessment of bone maturation and mineralisation.

Bone Diseases, Developmental↗