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Biomedical subjects

G K Jimerson

Publications and source records attributed to G K Jimerson.

11 recordsLinked to original sources

Ectopic pregnancy: a 15-year review of 160 cases.

Our review of the incidence of ectopic pregnancy in metropolitan Oklahoma City hospitals from 1960 through 1975 revealed an overall statistically significant increase. Review of the incidence of gonorrhea during the same period for the State of Oklahoma also showed a statistically significant increase. There was a significant correlation between the incidence of ectopic pregnancy and the incidence of gonorrhea. The 160 cases of ectopic pregnancy from University Hospital reviewed in detail included all ectopic pregnancies admitted from 1960 to 1975. Findings revealed 56% were white women with an average age of 26.8 years and average parity of 2.49. Pain (97.5%), amenorrhea (83%), and abnormal uterine bleeding (68%) were the most common presenting complaints, while abdominal tenderness (85%) and pelvic mass (54%) were the common physical findings. Culdocentesis was positive in 78% of the patients. Thirty-nine percent had a history of pelvic inflammatory disease and 8% a previous ectopic pregnancy. Admission diagnosis was correct in 67%. Unilateral adnexal procedure was the treatment in 81%. Fifty-seven percent of the ectopic pregnancies were right-sided, and hemoperitoneum averaged 950 ml. Postoperative complication rate was 55%. Follow-up pregnancy rate was 50%, and future ectopic pregnancies occurred in 6% of these.

Adolescent↗

Ovarian extraembryonal teratoma. II. Endodermal sinus tumor mixed with other germ cell tumors.

From the files of the Emil Novak Ovarian Tumor Registry, 18 cases of mixed ovarian germ-cell neoplasms containing endodermal sinus tumor as one element have been reviewed. The data regarding the patient age, presenting symptoms, gross appearance of the tumors, and response to therapy are similar to those reported in a previous series of pure endodermal sinus tumors. Response to all modes of therapy is disappointing but there is growing evidence that combination chemotherapy should be added to surgical excision as a routine part of therapy in such patients. The rarity of this lesion is such that meaningful data are likely to be available only if individual and institutional experiences are combined in central tumor registries.

Adolescent↗

Ovarian extraembryonal teratoma. I. Endodermal sinus tumor.

Forty-one cases of pure endodermal sinus ovarian tumors are reported. The extraembryonal nature of this tumor is supported with comparative studies utilizing early human implantations. The clinical picture is one of a virulent malignancy occurring in young women, and although the tumor is commonly unilateral and encapsulated at the time of initial diagnosis, the outcome is almost always fatal. Experience with different therapeutic modalities is limited, but there is significant evidence that vigorous combination chemotherapy will improve the therapeutic outcome.

Adolescent↗

Evaluation of abnormal cervical cytology.

The results from cytologic, colposcopic, and histologic studies in 376 patients are analyzed and compared to previous reports. Cytologic results correlated within 1 degree of the histologic diagnosis in only 67% of cases. Colposcopic impression correlated with the final histologic diagnosis in 78% of cases. Directed biopsies were exceedingly accurate (99.3%) when the entire transformation zone was visualized. When the entire zone was not visualized, 7 cases of invasive carcinoma were discovered among 59 cone biopsies. It is concluded that cytology should be used only as a screening tool and colposcopy as a directional aid in obtaining biopsies and defining the need for endocervical curettage. When the entire zone is visualized, directed biopsies are dependable and cone biopsies may be avoided. When the upper zone is not visualized and the endocervical canal is involved by significant dysplasia or carcinoma in situ as diagnosed by directed biopsies and/or endocervical curettage, cone biopsy is mandatory prior to definite therapy.

Biopsy↗

The rape victim: a review of 117 consecutive cases.

The case records of 117 women examined at University Hospital for the complaint of alleged rape have been reviewed. The usual victim was white, single, under the age of 25 years, and attacked by a single assailant. Fifteen patients sustained serious physical injury, and 60 received minor injuries. Six children required hospitalization for reparative surgery. One patient required hospitalization for 9 days secondary to severe emotional stress. The number of attacks was lowest in the daytime and highest from midnight to 6:00 AM. Cultures from the endocervix were positive for gonorrhea in 12% of rape victims. Unfortunately, it would appear from public records that there is little hope of the attackers being convicted.

Adolescent↗

Management of postoperative introital and vaginal stenosis.

Five patients with symptomatic postoperative introital or vaginal stenosis were evaluated and treated. In each case simple operative correction, utilizing basic plastic surgery principles, was successful. The five operative techniques as used alone and in combination are described. Though postoperative stenosis of the vagina and/or introitus is relatively uncommon, the resulting disability is such that every gynecologic surgeon should be familiar with the problem and solution. In most cases simple surgical correction can be successful if the surgeon is familiar with basic techniques and principles.

Aged↗