Biomedical subjects
Publications and source records attributed to G Jonderko.
TSH stimulation tests were performed in 17 patients with gastric or duodenal ulcers. Before testing patients were given either 400 micrograms of misoprostol orally or placebo. TSH, T3, and T4 secretion after TRH was assessed. No significant effect of misoprostol on TSH, T3, and T4 secretion was found.
Changes in serum cholesterol and aminoterminal type III procollagen propeptide (PIIIPN) were compared in 33 patients with hyperthyroidism, 16 patients with hypothyroidism, and 23 healthy individuals. An increase in PIIIPN was found in patients with hyperthyroidism and an increase in serum cholesterol level was associated with hypothyroidism. There was no correlation between investigated indices. It is suggested that PIIIPN changes were a result of altered connective tissue metabolism, while serum cholesterol was related to the intensity of body metabolism.