Search PubMed⌕ Search

Biomedical subjects

G Jenzer

Publications and source records attributed to G Jenzer.

13 recordsLinked to original sources

[Tension headache and migraine--management in general practice].

Tension type headache, migraine, and chronic daily headache as a possible endpoint of both, are the most frequent manifestations of primary headache. Their effects on the quality of life and at the workplace, as well as the socioeconomic consequences, are largely underestimated. The aim of treatment is the elimination of the condition or at the very least an acceptable improvement for the patient. If self-help fails, a professional approach is needed, priority being given to exclusion of symptomatic secondary headache and the necessary diagnostic classification in order to initiate treatment. These are primarily general measures, although often medication is indispensable. Empathic use of current knowledge, employing optimal means and methods, offers the best chance of success.

Combined Modality Therapy↗

[Clinical aspects and neurologic expert assessment in sequelae of whiplash injury to the cervical spine].

Whiplash injury to the cervical spine and its possible long-term sequelae, the late (or chronic) whiplash syndrome, are analysed based on a clearly defined accident mechanism and an initial battery of investigations to exclude lesions other than those affecting the soft tissue of the neck region (i.e. the consequences of strain and sprain). Predictors are discussed that may point to a delayed and complicated recovery, with development of a complex array of symptoms. The pattern of this symptomatology, as reviewed on the basis of different neuropsychological investigations, appears inhomogeneous. Comparison with other non-traumatic conditions, such as the chronic fatigue syndrome, the fibromyalgia syndrome and chronic daily headache, as well as with chronic disturbances of cervical origin, reveals striking similarities. In cases of litigation, these circumstances require careful assessment of the patient's previous history and an extensive differential diagnosis. Whiplash injury to the cervical spine rarely results in disability and, if so, is only minor.

Cervical Vertebrae↗

[Determining the status of the cervical spine after whiplash injury].

The results of medical investigations following acceleration mechanism to the cervical spine (so called "soft tissue neck injury") are to be described in common diagnostic terms. Biomechanical and legal considerations are beyond medical competence. In certain cases, the clinical examination must be completed in cooperation with specialists. Within the entire medical context, the neuropsychological and neuropsychiatric assessment may contribute to a comprehensive understanding of the consequences. In cases of litigation, the full array of facts, like the patients' previous history, and differential diagnoses, have to be drawn to attention. At present, compensation takes place only exceptionally and in a limited range, if an impairment by an accompanying brain injury is excluded.

Accidents, Traffic↗

[The "severity" of "whiplash injury of the cervical spine"].

The severity of the so called "whiplash injury of the neck" ("soft tissue neck injury") and the condition thereafter depends on the chosen angle of view: impact dynamics, biomechanics, pathological-anatomical considerations, clinical and apparative findings, medicolegal aspects and subjective assessment. The impact itself may not serve as a diagnosis, which latter has to be founded on the results of the medical examination. These findings seem to be appropriate for the resolution of questions in the course of litigation. At present, a universal severity may not be defined.

Accidents, Traffic↗

[Dihydroergotamine as a nasal spray in the therapy of migraine attacks. Efficacy and tolerance].

In an open multicentre study in Switzerland, the dihydroergotamine nasal spray was studied for its efficacy and tolerability in the treatment of acute migraine attacks (common and classical migraine--one attack each patient) in a total of 904 patients. In the global assessment, 76.8% of all the patients reported good efficacy (freedom from pain, less pain or shorter duration of pain). When the nasal spray was used already in the prodromal phase, good efficacy could be obtained by 90 (63%) of 143 patients. 18.1% of all the patients treated--more frequently those who obtained no beneficial effect and/or who took additional medication during the migraine attack--reported one or more--minor side-effects such as local nasal irritation (congestion, burning or stinging), nausea, dizziness and vomiting. 3.9% of the patients said they would not use the spray again because of the side effects.

Administration, Intranasal↗

Ocular involvement in benign botulism B.

In nine cases of botulism B infection due to food poisoning acute onset of accommodation paresis, mydriasis, and dry-eye symptoms were the prominent clinical findings. Impairment of salivary secretion as a further effect upon cholinergic autonomic innervation was detectable for months. Guanidine treatment had a beneficial effect, whereas administration of antitoxin in the late and benign form was not effective.

Accommodation, Ocular↗

Autonomic dysfunction in botulism B: a clinical report.

Nine cases of botulism B with preponderant effects upon cholinergic autonomic innervation are presented. Blurred vision and dry mouth were constant symptoms. Impairment of salivary and lacrimal secretion were detectable for months. In the absence of clinical signs, electromyographic studies did not reveal neuromuscular involvement. Administration of antitoxin in the late course of such cases is not recommended, but guanidine can be used. Doubt is cast upon a new clinical entity called "acute autonomic neuropathy."

Adult↗