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Biomedical subjects

G Janczewski

Publications and source records attributed to G Janczewski.

At least 55 records · Page 3Linked to original sources

Studies on the temporary effect of noise on the auditory function in man.

ECoG and ABR recordings were performed on 22 young, normal-hearing persons, before and after exposure to fatiguing noise. Temporary Threshold Shift (TTS) of up to 35 dB at 4-6 kHz was induced by octave band noise with centre frequency at 2.8 kHz. The latency of waves I, III, V and ACAP (Auditory Compound Action Potential) and intervals between waves I-III, III-V, I-V and ACAP-V were analysed as functions of stimulus intensity in pre- and post-exposure recordings. In post-exposure recordings a threshold elevation, a significant increase of latency and unaltered intervals between the successive waves and ACAP were observed. It was concluded that the noise-induced auditory fatigue, measured as TTS, originates within the cochlea and is transferred to the auditory pathways. The great intersubject variability of the data obtained indicates that the TTS may be a useful measure of individual sensitivity to noise, but prognosis on the presumed Permanent Threshold Shifts (PTS) based on the evaluation of TTS would seem doubtful.

Auditory Fatigue↗

[Occupational allergy in miners].

The authors allergologically analysed 141 coal miners afflicted with upper respiratory tract inflammations. In 7% of cases the disease was found to be induced by coal dust. All the subjects exhibited positive dermal tests with common allergens (plants pollens, household dust, saprophytes, moulds). The authors suggest that atopic status may contraindicate the work in coal mining. 57% of cases exhibited changes in the nose inhibiting its patency (hypertrophy of nasal concha, nasal mucosa polyps, lateral deviation of the nasal septum).

Adult↗

[Acoustic nerve adaptation in chronic acoustic trauma].

The adaptation phenomenon of the the cochlear nerve in the highest frequency region was studied by means of electrocochleography in the group of 32 persons exposed to prolonged noise and with noise-induced, mild hearing loss (in the 4--6 kHz region) and in 19 persons under the same conditions of noise-exposure but, without any evidence of the hearing loss. The same investigations were performed in the group of 27 normal-hearing persons and non-exposed to noise. In the whole group of persons exposed to prolonged noise, disregarding their hearing condition the amplitude-decrease of the action potential of the cochlear nerve due to the adaptation procedure, was twofold in comparison to the non-exposed persons. The latency of this potential was longer in the whole group of exposed to noise persons than in the intact persons. It was presumed that this type of auditory nerve adaptation results infinitial, ultrastructural noise-damage within the basal turn of the cochlea. Basing on the obtained results it was postulated that the adaptation phenomenon in the highest-frequency region can serve as an indicator of early noise-induced malfunction of the cochlea which probably precedes the highest-frequency threshold elevation in conventional audiometry.

Adaptation, Physiological↗