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Biomedical subjects

G J Roberts

Publications and source records attributed to G J Roberts.

At least 91 records · Page 5Linked to original sources

Growth of the cartilages of the mid-line cranial base: a radiographic and histological study.

The importance of controlling litter size in growth studies is verified for Rattus norvegicus. A method of studying growth of the cranial base bones in the median sagittal plane is described and figures for growth rate in micrometres per day have been produced for the age range 4-480 days. The age range 4 to 80 days is identified as the period when 50% of growth takes place and therefore as a period which is particularly useful for growth studies. The presence of a caudorostral gradient in growth rate is suggested by the results. The nomenclature of the cell zones in endochondral growth sites is reviewed and the use of the term matrixogenic is offered to describe and identify more accurately one of the functional zones in endochondral growth sites.

Animals↗

Dental treatment in young handicapped patients. An assessment of relative analgesia as an alternative to general anaesthesia.

A trial was undertaken to assess the suitability of oxygen/nitrous oxide sedation (relative analgesia) for dental treatment in unmanageable handicapped young patients. Fifty patients with chronological ages 5-22 years and mental ages 1 1/2-14 years participated in the double blind trial to see if premedication with diazepam 0.2 mg/kg would be a useful adjunct. After the trial, previous dental histories and behaviour at regular recall visits over the next 12-18 months were studied. Seventeen of 19 patients previously treated with general anaesthesia and 27 of 31 formerly untreated patients accepted treatment in the trial; of the 50 patients, 33 are continuing treatment with oxygen/nitrous oxide sedation, seven need general anaesthesia and 10 have moved from the district. It appears that the use of diazepam premedication improves patient demeanour and operating conditions although this improved effect is not carried over to recall visits. The results obtained indicate that routine dental procedures can be safely carried out by an experienced operator-sedationist in young handicapped patients using oxygen/nitrous oxide sedation. The frequency with which potentially hazardous techniques need to be used can be reduced, as can hospital admissions.

Adolescent↗

Inhalation sedation.

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Anesthesia, Inhalation↗

Relation between medicines sweetened with sucrose and dental disease.

The teeth of 44 children aged under 6 years who had been taking syrup medicines regularly for at least six months were compared with those of a control group of 47 children of similar ages. Dental disease was assessed by measuring dental caries, dental plaque, and gingivitis. The children who were receiving sucrose-based medicines had significantly more carious teeth and gingivitis. It is concluded that sucrose-based medicines continuously administered to children cause dental caries and gingivitis. Liquid medicines for children should be either unsweetened or sweetened with non-cariogenic substances.

Administration, Oral↗