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Biomedical subjects

G Ito

Publications and source records attributed to G Ito.

At least 55 records · Page 3Linked to original sources
PubMed1989

[Follow-up study of bone grafts to the alveolar clefts].

Clinical follow-up study after the grafting with fresh autogenous iliac bone to the alveolar clefts in cleft lip and palate patients was carried out up to 2 years post operation. Twenty two patients were examined, to whom grafts of iliac cortical or iliac marrow bone was carried out by the First or the Second Department of Oral Surgery, Kagoshima University Dental School from July, 1985 to April, 1988. Their cleft types were classified as 18 unilateral and 4 bilateral cleft lips and palates. The ages at bone grafting were ranged from 8 years 9 months to 17 years 6 months, and the average of which was 12 years 3 months. Nine of these patients were grafted with the cortical bone, and the other 13 were grafted with the marrow bone. The perforations at alveolar clefts were covered with the tongue flap in 10 clefts of 10 patients, while they were covered with the local mucous flap in 15 clefts of 12 patients. Among these patients, dental casts, X-ray radiograms and oral pictures of 15 patients were surveyed postoperatively. Results were as follows: 1) Contours of the alveolar clefts were well corrected in 9 patients, especially in those cases of pre-operatively expanded unilateral clefts, grafted with the marrow bone and covered with the local mucous flaps. 2) The viable rate of grafted bone was 100.0% for the marrow bone, while it was 62.5% for the cortical bone.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1988

[Correlations between masticatory performance in chewing gum method and occlusion as well as dento-facial morphology].

In order to examine the characteristics of the chewing gum masticatory test, the amount of sugar elution, the chewing time and the amount of sugar elution per second were measured in 109 young adults (93 males and 16 females), after 70 strokes of mastication. Their sex differences, differences among various occlusions, correlations with occlusal areas of the buccal teeth and correlations with roentgen cephalometrics were analyzed. 1. There was no sex difference in the amount of sugar elution. However, chewing time was shorter and the amount of sugar elution per second was higher in males than in females. 2. Compared with the normal occlusion group, the amount of sugar elution was significantly lower in the crowding and anterior cross bite groups (Inoue's classification), and in the Class III malocclusion group (Angle's classification) in males. The amount of sugar elution per second was also significantly lower in the crowding and anterior cross bite groups. However, significant differences could not be found for chewing time. 3. The amount of sugar elution per second was significantly correlated with occlusal areas in males and total samples. 4. The amount of sugar elution was significantly correlated with less than ANB and less than L 1 to MP in males, with less than L 1 to MP in total samples. The chewing time was significantly correlated with S-N, N-Me, N-ANS, S'-Ptm' in females. The amount of sugar elution per second was significantly correlated with less than SNA and less than L 1 to MP in males, and with A'-Ptm', Cd-Go, Go-Pog', Cd-Gn, less than SNA, less than L 1 to MP, less than MP-SN and gonial angle in total samples. 5. It is concluded that the chewing gum masticatory test is highly correlated with occlusion and dento-facial morphology. In particular, amount of sugar elution per second was thought to be a useful measure for masticatory performance in clinical orthodontics.

Chewing Gum↗
PubMed1988

Effect of soft diets on craniofacial growth in mice.

The 300 C3H/He strain male mice were divided into 3 groups; solid, kneaded, and liquid diet groups. Each group was consisted of 5 cross-sectional subgroups, i.e. 3, 5, 7, 12 and 20 weeks subgroups. X-ray pictures of their craniofacial complex were measured to investigate the extent and time that growth retardation can be recognized in the cranium. As the results, soft diets could retard craniofacial growth, although it accelerated body growth. Increase of height and depth of distal part of mandible and all 3 dimensions of craniofacial complex were affected by taking soft diets through the growing period. Some of them were apparent even in weaning period. As the distal areas of both craniofacial complex and mandible are closely related to jaw function, growth retardation of this area could be explained as the skeletal adaptation to the soft diets.

Animals↗
PubMed1987

A histological comparison of the tissue interface of bioglass and silica glass.

The objectives of the present article are to confirm the bone bonding phenomenon of Bioglass (BG) developed by Hench et al., and to observe the singularity of tissue reaction to it. BG and nonreactive silica glass (SG) were implanted in the femurs of rabbits and rats. Histological examination revealed that a relatively acellular zone with little inflammation was formed on BG surface at 1 day after implantation. Neither fibrous tissue nor a distinct boundary was observed between BG and bone after 7 days. On the contrary, a moderate postoperative inflammatory reaction was observed on SG at 1 day, and fibrous tissue was observed between SG and bone after 7 days. From these findings, it was confirmed that BG bonded directly with bone. As the relatively acellular zone observed on BG surface at 1 day was replaced by bone after 7 days, the formation of this zone might play an important role in bone-bonding process. Further research should be focused on the mechanism and biological meaning of bone bonding, for this phenomenon can not be explained by the conventional pathological theory of foreign body encapsulation.

Animals↗
PubMed1987

The influence of bioglass on the growth of fibroblasts.

The influence of Bioglass (BG) on the growth of L cells was studied by means of tissue culture, to get an idea on its bone-bonding mechanism. Growth rate of L cells on BG was lower than that on the control silica glass (SG). L cells on BG diminished in size and took up long and slender polygonal shapes with radially spread long pseudopods, which probably meant that the cell cycle was detained at the synthetic period. From these findings, BG is thought to have an inhibitory effect on the growth of L cells, which might arrest the fibrous tissue encapsulation and allow bonding with bone.

Animals↗
PubMed1983

Influence of tooth-to-denture-base discrepancy on space closure following premature loss of deciduous teeth.

Influence of tooth-to-denture-base discrepancy on so-called physiologic migration of the first molar was studied on serial dental casts of 116 boys and girls, obtained through a dental health program for school children in an area in which there was no dentist. The alteration of spaces following premature loss of deciduous molars was examined comparing the anterior to posterior discrepancies between tooth and denture base. Modes of space alteration showed positive correlation with the size of the discrepancy, especially in the mandibular dental arches. The space deficiency in the posterior region seemed to have a positive effect on the mesial migration of the first molar. Mesial migration of the first molar seems to be pathologic rather than physiologic and is strongly affected by tooth-to-denture-base discrepancies. Space maintenance does not seem to be useful, because it is not necessary in minimum discrepancy cases and is not effective in severe discrepancy cases.

Adolescent↗