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Biomedical subjects

G Irsy

Publications and source records attributed to G Irsy.

28 records · Page 2Linked to original sources
PubMed1978

Oddi's sphincter spasm in hypocalcaemia of dogs.

1. Decreases of serum calcium concentration in dogs lead to increased basal tone of Oddi's sphincter in the employed experimental model. 2. This effect is independent of the agent used for decreasing the serum calcium level. 3. Spasmolysis was observed immediately after the injection of CaCl2. CaCl2 alone, however, had no effect in "normocalcaemic" animals. 4. Local decrease of calcium level plays no significant role in the sphincter spasm. It is suggested that the spasm is elicited by increased smooth muscle excitability as a consequence of the hypocalcaemic state prevailing in the body.

Ampulla of Vater↗
PubMedDate not supplied

[The role of several simultaneously acting mechanisms in the formation of the clinical symptomatology of Goodpasture's syndrome].

Two cases of Goodpasture syndrome in young patients are described; the importance of a detailed analysis of the symptoms is stressed and found useful in explaining the origin of simultaneous manifestations of allergic reactions of different mechanisms. Thus a wider variety of therapeutical possibilities may be applied and better allowance made for the nature of diseases. An analogy is assumed between the occurrence of the symptoms described and of the development of auto-immune diseases which have not, or only with difficulty, been differentiated.

Adolescent↗
PubMedDate not supplied

[Infectious and neoplastic complications in rheumatoid arthritis].

Three cases are reported of rheumatic arthritis protracted over several decades, with reduced immunobiological resistance, who developed infectious arthritis, a syndrome with urticaria and angio-edematous signs and increased monoclonal IgM synthesis, and Hodgkin's disease. The discussion covers the manifold pathogenesis, the common and simultaneous effect of constitutional, local factors of the development of the disease, related to the generally reduced resistance of the organism, and the therapeutical moments (corticosteroids, immunosuppressives); further the establishment of therapeutical measures in the interest of the prevention of the complications mentioned.

Aged↗