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Biomedical subjects

G Iacono

Publications and source records attributed to G Iacono.

At least 109 records · Page 6Linked to original sources

[Prognosis of acute hepatitis B].

The clinical course, persistance of HBs antigen, and the liver biopsy morphological picture were evaluated in 40 patients with acute viral hepatitis, type B. In 34 cases, the disease ran a satisfactory course and clinical cure was corroborated histologically. In 4 cases, onset was particularly severe and the disease ran a long course. Here the immunological test for HBs antigen was still positive 8 weeks after the disease began, while a biopsy at 4 months showed a morphological picture similar to that of acute hepatitis. Lastly, two cases with a protracted clinical course displayed persistent HBs antigen positivity one year after the acute episode, with a histological finding of persistent hepatitis and cirrhosis of the liver respectively.

Biopsy, Needle↗

[Antigens and antibodies in acute viral hepatitis caused by the B virus. Clinical significance].

Three antigen-antibody systems are so far known to be related to viral hepatitis type B. Tests for evidencing HBsAg and antiHBs are easily performed and important for the diagnosis, prevention and study of hepatitis B. The tests for evidencing HBcAg and HBc are still the subject of study and research. The presence of HBsAg in a subject shows he is hosting hepatitis B virus. It may also be present without hepatopathy or it may be associated with acute or chronic hepatitis B. At the present time there is no feasible way of eliminating the chronic carrier condition. The problem represented by healthy carriers as infection risks is currently under study.

Antibodies, Viral↗

[Effect of metoclopramide on growth hormone (GH) release induced with ACTH].

We examined 10 volunteers subjects, sound and exempt from endocrine disease. The rapid injection of 0,25 mg of ACTH (Synacten) was followed by a distinct increase of plasma Growth Hormone (GH) within 30 or 60 min in 9 of 10 normal volunteers. The test were then repeated in the 12 "responders" after previous subministration of Metoclopramide and the GH response was totally abolished.

Adrenocorticotropic Hormone↗

[Effect of TRH on growth hormone (GH) release induced with ACTH].

We examined 14 volunteers subjects sound and exempt from en docrine disease. The rapid injection of 0,25 mg of ACTH (Synacten) was followed by a distinct increase of plasma Hormone (GH) within 30 or 60 min in 12 of 14 normal volunteers. The test were the 12 "responders after previous subministration of 200 g of TRH and the GH response was totally abolished.

Adolescent↗

[Functional diencephalo-pituitary diagnosis by means of radioimmunoassay].

The Author, after mentionating the always increasing need of cooperation between the clinical activity and the laboratory research, stops considering the semeiological meaning of the radioimmunoassay of the pituitary hormones. However he worns against the limitations that such dosages present at the base line and the possible dissociation between immunological activity and biological activity. He describes then the dynamic tests able to determine variations of hormonal levels and makes his conclusions stating that the observation made during dynamic conditions may be of help to the clinical diagnosis.

Adolescent↗