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Biomedical subjects

G Ia Maslennikova

Publications and source records attributed to G Ia Maslennikova.

8 recordsLinked to original sources
PubMed1989

[Atherogenic dyslipidemia in adolescents: its relation to ischemic heart disease in their fathers and the possibility of its prognosis].

Comparison of a group of adolescents aged 11-16 years whose fathers had angiographically documented coronary atherosclerosis in youth with those matched by sex and age whose parents were clinically healthy yielded the following discriminant function (DF) involving lipid and apoprotein indices of the plasma lipid system: DF = [apo B] X 0.03-[HDL cholesterol] X 0.04-0.81. DF greater than or equal to 0 discriminates from the controls 32% of the offsprings from the fathers with a history, DF less than 0 correctly classifies 98% of adolescents from the controls. The adolescents who have DF greater than or equal to 0 amounted to about 19% in representative samples of Moscow adolescents. Moreover, DF with 80% probability makes it possible to predict the time course of serum lipid levels in adolescents within 2 years.

Adolescent↗
PubMed1987

[Changes in the basic risk factors for ischemic heart disease in Moscow boys over the period of a year: natural dynamics and the effects of prophylactic action].

The rise in mean blood plasma levels of total cholesterol, LDL cholesterol and VLDL cholesterol over a one-year period has been observed in Moscow boys (aged from 12 to 13 years). Mean systolic blood pressure (SBP) in this period remained unchanged. In the district where preventive therapy was performed we have observed the decrease in mean levels of total cholesterol, LDL cholesterol, VLDL cholesterol and SBP over a one-year period in boys of the same age group. Age-dependent increment in Ketle index was significantly lower in this district. This indicates that preventive measures have a positive effect on the formation and development of CHD risk factors in children.

Blood Pressure↗
PubMed1987

[Relation of the levels of thyroid hormones and cortisol and the degree of systolic arterial pressure in 11- and 12-year-old boys].

An epidemiologic evaluation of relationships between arterial BP changes, and thyroid and adrenocortical hormones was carried out in eleven- and twelve-year-old boys. Different patterns of correlation were demonstrated between plasma thyrotropic hormone, thyroid hormones and cortisol levels, on one hand, and systolic BP variation, on the other. There was a correlation between thyroid hormones and cortisol in these groups. The results suggest that even slight changes in thyroid and adrenal function may promote disorders of BP regulation.

Age Factors↗
PubMedDate not supplied

[Role of sex hormones in the development of atherogenic dyslipoproteinemia in boys of pubertal age].

Interrelationships of hypercholesterolemia (HCS), hypertriglyceridemia (HTG) or hypo-alpha-cholesterolemia (hypo-CS HDL) and the blood levels of sex hormones were investigated in boys aged 14-15 to detect variations in the levels of sex hormones to define groups of adolescents at the highest risk of developing atherogenic dyslipoproteinemia (DLP). A conclusion has been made that HCS and hypo-CS HDL development is associated with changes in the blood levels of testosterone and estradiol, and a low blood level of T in HTG is of secondary origin with regard to the development of this type of DLP.

Adolescent↗