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Biomedical subjects

G Howard

Publications and source records attributed to G Howard.

At least 253 records · Page 14Linked to original sources

Motivation for vasectomy.

Men under 35 tend to request vasectomy for different reasons from those given by older men. Potential sexual, marital, or ageing problems seemed to motivate older couples, and problems related to family size, recent pregnancy, and difficulty with contraception the younger ones.

Adult↗

Occurrence of ovulation in women receiving the injectable contraceptive norethisterone oenanthate.

Ovarian function was studied in ten women receiving a single intramuscular injection of 200 mg norethisterone oenanthate. Two of the ten women appeared to ovulate within 60 days of injection and a further four within 90 days. Follicular activity probably not followed by ovulation occurred in five subjects within 60 days of the injection and in a further subject within 90 days. Only one subject showed no evidence of follicular or luteal activity during the course of this study. There was wide variation in the rate at which the administered gestagen was metabolised and no correlation between the rate of metabolism of norethisterone and the return of ovarian function or the ponderal index, height or weight of the subjects.

Adult↗

Transient ischemic attacks: a prospective study of 225 patients.

Between the years 1964 and 1973, 225 patients with transient ischemic attacks (TIAs) due primarily to atherosclerosis were evaluated and treated. They have now been followed for from 3 to 14 years (average 5.5 years). As of 1976, 82 of the 225 patients were dead, 21 from cerebral infarction, 52 from heart disease and nine from other causes. Of the 56 untreated patients, 11 (19 percent) had cerebral infarctions, four (7 percent) of which were fatal; six (11 percent) were still having TIAs. Of the 45 patients medically treated, 10 (24 percent) had cerebral infarctions, three (7 percent) of which were fatal; 11(25 percent) still experienced TIAs. In the surgical group of 124, 27 (21 percent) had postoperative cerebral infarctions, seven (6 percent) of which were fatal; 23 (18 percent) had cerebral infarctions during follow-up, of which seven (6 percent) were fatal; and 15 (12 percent) were still having TIAs. No statistically significant differences (p less than 0.05) related to cerebral infarction or TIAs developed among the three groups. The majority (23 percent) eventually succumbed to myocardial infarction, leading us to conclude that great emphasis must be placed upon TIAs as a warning for cardiac as well as cerebrovascular disease.

Aged↗

Effect of dose and dose schedule on the response of intracranial pressure to mannitol.

Analysis of monitoring records of 150 patients given over 1000 infusions of 20% mannitol delineared three variables affecting the response of intracranial pressure (ICP) to mannitol: the original ICP; the current dose; and the dose given over the preceding three hours. The level of ICP influenced the response to mannitol as much as the amount of mannitol; giving more mannitol than was required to bring ICP below 25 mm Hg led to the need for larger following doses. One hundred-milliliter-bolus doses were often as effective as larger doses. The results suggest that doses of mannitol given to control increased ICP should be kept as small as possible.

Humans↗

The right to vote and voting patterns of hospitalized psychiatric patients.

Hospitalized psychiatric patients have traditionally been denied their right to vote. This right was restored in 1972 when the Queens Board of Elections established a registration and polling site on the Creedmore Hospital grounds. A patient education program stimulated interest in current affairs and facilitated informed voting. Gross analysis of patient-voting patterns showed no significant difference from the community at large. However, deeper analysis suggests that the patient vote was independent of the borough of residence, tending to be more Democratic-Liberal and less Republican-Conservative. Furthermore, the patient vote was seen to reflect thoughfulness and awareness of relevant self-interest.

Attitude↗

The effects of intramuscular norethisterone oenanthate used as a contraceptive on intravenous glucose tolerance and on blood coagulation factors VII and X.

Intravenous glucose tolerance tests, and estimations of prothrombin time, and plasma coagulation factors VII and X, were made on 12 women receiving 200 mg norethisterone oenanthate intramuscularly as a contraceptive. These estimations were made before, and at 2 and 12 weeks after, a single injection of norehisterone oenanthate. There was no significant effect on the intravenous glucose tolerance, prothrombin time, or on plasma coagulation factors VII and X, further confirming the safety of norehisterone oenanthate when used as a short-term injectable contraceptive.

Blood Coagulation↗

Binding of thiostrepton to ribosomes from thiostrepton-sensitive and -resistant Bacillus subtilis strains.

Binding of [(35)S]thiostrepton to ribosomes from thiostrepton-sensitive and -resistant strains of Bacillus subtilis was studied. Ribosomes from thiostrepton-resistant strains bound relatively little thiostrepton compared with ribosomes from thiostrepton-sensitive B. subtilis. In addition, ribosomes from revertant strains that were obtained as thiostrepton-sensitive revertants from thiostrepton-resistant strains bound [(35)S]thiostrepton similarly to ribosomes from the sensitive parental strain.

Anti-Bacterial Agents↗

The ex-mental patient as an employee: An on-the-job evaluation.

In light of studies showing negative employer attitudes toward ex-mental patients, a comparative study was made of ex-patient employees and non-disabled employees. Results showed ex-patients indistinguishable from randomly selected employees in job performance, human relations, and overall rating. These findings are discussed in terms of the general employability of the mentally restored. The work project studied is offered as a model.

Absenteeism↗

Pill or IUD?

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Adolescent↗