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Biomedical subjects

G Hirose

Publications and source records attributed to G Hirose.

At least 109 records · Page 6Linked to original sources
PubMed1980

Intramedullary spinal cord metastasis associated with pencil-shaped softening of the spinal cord: case report.

A 57-year-old man presented with a pulmonary mass and subacute onset of paraplegia. Laboratory examination revealed an increased protein content in the cerebrospinal fluid and a normal myelogram. Autopsy disclosed epidermoid carcinoma in the left lower lobe of the lung, intramedullary metastasis at the midthoracic level, and a central pencil-shaped softening above and below the metastatic lesion. The pencil-shaped softening was an ischemic infarct rather than of hemorrhagic or congestive origin. The pathogenesis of this rare association may be explained by the hypothesis of a tumor embolus in the arterial circulation that feeds the center of the cord, producing metastasis. This embolus was followed later by a second embolus to a radicular artery, causing the pencil-shaped softening of the spinal cord.

Carcinoma, Squamous Cell↗
PubMed1979

Spinal cord ischemia and left atrial myxoma.

A 62-year-old man had an acute, transient, flaccid paraplegia. Examination showed a primary cardiac tumor with emboli to major branches of the aorta. A myxoma was removed from the left atrium, and normal function returned. Left atrial myxoma should be suspected as a cause for embolism to the CNS.

Embolism↗
PubMed1979

[Ossification of the posterior longitudinal spinal ligament--comparative studies with computerized tomography (author's transl)].

Ossification of the posterior longitudinal spinal ligament (OPLL) was characterized by calcified longitudinal band along the posterior margin of vertebrae, but it has not been possible to know how the cord is compressed within the narrowed spinal canal. Our neuroradiological studies based on CT-view of the 15 cases of OPLL suffering from various degree of myelopathy revealed: 1) Computed tomography precisely delineated shape of OPLL, which was quite polymorphic, like mushroom, irregular cubic and round. OPLL ranged more than two vertebrae was not uniform, but exhibited different configuration at each level. 2) OPLL at lower cervical and higher thoracic regions was difficult to diagnose by conventional lateral roentgenograms, but CT-scan demonstrated clearly whole extent of OPLL. 3) obliteration ratio of the affected spinal canal was calculated on CT-scan. Cases showing severe myelopathy, such as quadriparesis and neurogenic bladder, presented spinal canal stenosis of more than 30%. Spondylosis were concomittant roentgenographic findings on 13 cases of OPLL (87%). However, spondylotic changes responsible to the myelopathy were seen on only three cases. In these case, the obliteration ratio by ossificated ligament was lower than 26%. On conclusion, computed tomographic views of OPLL gave us more detailed information about the stenotic spinal canal and found to be essential examination when considering operative intervention.

Aged↗
PubMed1978

Origin of the retina from both sides of the embryonic brain: a contribution to the problem of crossing at the optic chiasma.

Cells originating from one of the first two blastomeres of the frog embryo were labeled either by injecting them with horseradish peroxidase or by changing the ploidy of one blastomere. Both methods show the labeled cells confined to the same side of the brain as the labeled blastomere except for cells that have moved from the opposite side into the ventral diencephalon and ventral part of the retina. Reciprocal movement of cells from each side of the prospective forebrain into the prospective retina on the opposite side starts before the neural tube closes and results in the formation of an incipient optic chiasma which may provide the pathway for optic axons to grow from the retina to the opposite side of the brain.

Animals↗
PubMed1977

Alexia without agraphia associated with right occipital lesion.

A 78 year old, right handed man developed the syndrome of alexia without agraphia due to a right occipital thrombotic stroke. The cerebral dominance test strongly suggests that his right hemisphere is dominant. This is believed to be the first case of alexia without agraphia secondary to a right occipital lesion in a right handed person.

Aged↗
PubMed1975

Transmission of a t(13q22q) chromosome observed in three generations with segregation of the translocation D1-trisomy syndrome.

A case of an inherited type of D/G translocation D1-trisomy syndrome was described. A female proposita who had the clinical signs of D1-trisomy syndrome was found to have a chromosome complement of 46,XX,--G,+t(DqGq). examination of Q- and G-stained karyotypes revealed that the chromosomes involved in the translocation were members of Nos. 13 and 22, or t(13q22q) with breaks at p12 of both chromosomes. C-stained figures also showed a large heterochromatin block in its centromeric region. The t(13q22q) chromosome was transmitted from the paternal grandmother of the proposita through at least three generations.

Abnormalities, Multiple↗
PubMed1975

Thalamic tumors in childhood. Clinical, laboratory, and therapeutic considerations.

Eighteen cases of primary thalamic tumor occurring in children (ages 2 1/2 to 12 1/2 years) were studied retrospectively. Among the clinical features of this group that contrasted with adults having similar tumors were a shorter duration of symptoms before diagnosis and a higher incidence of motor abnormalities in the early illness. In several cases, symptoms and signs usually associated with cerebellar disorders predominated. Arteriography or gas encephalography or both were diagnostic in all but two cases. The electroencephalogram, abnormal in slightly more than 70% of the cases, suggested a thalamic mass in more than one third. A highly specific EEG feature was the presence of spindles while patients were awake. In 15 cases there was some evidence of ventricular dilation and nine of these later required shunts. In addition to shunting procedures, therapy included x-ray therapy alone or with craniotomy or craniotomy alone.

Astrocytoma↗