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Biomedical subjects

G Hesse

Publications and source records attributed to G Hesse.

At least 37 records · Page 2Linked to original sources
PubMed1994

[Argon laser therapy of chondrodermatitis nodularis chronica helicis].

In 5 years 9 patients with a total of 16 painful ear nodules (chondrodermatitis helicis) have been treated as follows. A small excision is carried out with local anaesthesia for histological examination. The rest of the nodule or any other nodules are carbonized by means of the argon laser, also with local anaesthesia, including the surface of the cartilage under the nodules. There have been no cases of postoperative inflammation or infection. New nodules occurring several months after treatment have been successfully treated in the same way. There have been no real recurrences. The cosmetic result is very good in all cases. The patients are free of pain immediately after the laser therapy. Laser therapy for painful nodules of the ear has good and lasting results, with a lower rate of recurrences than any other form of treatment.

Adult↗
PubMed1994

[Microfilm documentation in follow-up of melanocytic tumors].

Microfilm photography allows documentation of naevi in a map-like fashion. The localization of multiple naevi is no longer a problem, as one can scan the film. Comparison of the magnified film with the patient can be done in day-light. Magnification up to 48 times is possible. Detection of early changes of the naevi, during the horizontal growth phase, should increase the 5-year survival rate.

Cell Transformation, Neoplastic↗
PubMed1991

[Jena longitudinal study of the growth of 0-3 year old children. 2: Percentile curves for body height, body weight, height related weight and growth rate].

Charts for body length and height, body weight, and height- and weight velocity basing on a longitudinal study with 306 children from the newborn age to 3 years of age, are presented. Length and weight velocity are strongest in the time between the 4th and 8th week of life. From the first to the fourth trimester velocities decrease continuously.

Adolescent↗
PubMed1990

[Dehydration therapy in low tone hearing loss. An alternative to rheologic therapy?].

Patients with acute low-tone sensorineural hearing loss were treated by rheology or dehydration after recording of the summation and compound action potentials by electrocochleography. Patients treated in the acute phase, as well as patients with chronic disease (that is the interval between onset of hearing loss and therapy was more than 1 week) clearly responded better to dehydration than to conventional rheological treatment. This was especially striking in those patients showing an enhanced SP/AP ratio indicating endolymphatic hydrops.

Acetazolamide↗
PubMed1989

[Frequency-dependent cochlear microphonics in inner ear hearing loss with various pitch thresholds].

Promontory recordings of the cochlear microphonics (CM) after stimulation with 0.5, 1 and 2 kHz tone bursts at 120 dB SPL were performed on normal subjects and patients with various, levels of sensory hearing loss. A significant correlation was found between frequency-related CM amplitudes and the configuration of the pure-tone audiogram. Such recordings provide objective information on hearing abilities at low and middle frequencies and are thus a relevant tool in clinical audiometry.

Auditory Threshold↗
PubMed1988

[Sterile eosinophilic pustulosis (Ofuji)].

In recent years there has been an increase in the information available on "eosinophilic pustular folliculitis (Ofuji)". A significant feature of this disease is extensive tissue eosinophilia in association with follicular, intraepidermal or subcorneal pustules containing eosinophils. A review of the current literature reveals that the skin lesions vary widely. Some patients present with pustules on an erythematous base; in others, annular or circinate papulonodular lesions predominate, which may become crusted. Even vesicular lesions have been reported. The extensive tissue eosinophilia itself suggests that the condition is not caused by an exogenous infectious agent. Most data implicate an immunopathological event that is still not well understood.

Biopsy↗
PubMed1988

[Changes in the compound action potential in patients with acoustic neuroma].

Thirty-eight patients with proven acoustic neuroma were divided into three groups: 13 patients with normal threshold on pure tone audiogram, 15 patients with a hearing loss of 40 dB-80 dB (HL) in the low and middle frequencies, and 10 totally or almost deaf patients. Results of the first two groups are reported, using intra-tympanic electrodes with alternating clicks of 90 dB (nHL) intensity and a stimulus rate of 20/s. A total of 500 sweeps were averaged. Widening of the CAP complex by a mean of 1.6 ms, compared to 1.1 ms in normal hearing subjects, was the most striking finding. Summation potentials (ratio of SP amplitude to CAP amplitude) were enlarged to 0.6, compared to 0.2 in healthy persons and 0.9 in patients suffering from Ménière's disease. CAP amplitudes as well as CM amplitudes were reduced to almost one-third of normal values. The most noticeable result was the loss of amplitude using very short interstimulus intervals. With a stimulus rate of 97/s amplitudes of acoustic neuroma patients were reduced by 49.9% - reduction in normal and Ménière patients was 41.6% and 41.3%. Acoustic neuroma patients show pathological inner ear potentials. Increased summation potentials are often found with Ménière patients, which are said to be caused by endolymphatic hydrops. For tumours of the acoustic nerve the hydrops theory does not seem likely; the loss of amplitude due to ++adaptation++ within the first neuron seems to point to mechanical reasons due to the pressure of the tumour itself.

Auditory Threshold↗
PubMed1988

Magnetic resonance imaging (MRI) and high resolution computertomography (HRCT) in cochlear implant candidates.

Cochlear implant candidates must be thoroughly tested for their suitability pre-operatively. Electrical and electrophysiological tests as well as a psychological assessment are of fundamental importance in the selection process. The implantation of an intracochlear electrode requires specific information about the anatomy of the petrous bone and the endocochlear space. Such information can be obtained by using high resolution computed tomography (HRCT) or magnetic resonance imaging (MRI) using a surface coil. Over three years 438 patients were evaluated in our clinic as possible implant candidates. Out of these candidates 251 were evaluated using HRCT and 123 using MRI. In 39 (15.5%) cases we found bony abnormalities of the petrous bone using HRCT scans. 17 (13.8%) of the cases evaluated with MRI had no complete fluid filled spaces in the cochlea. Three patients who where identified as having ossified cochleas were subsequently implanted with an extracochlear device. MRI and HRCT have proved to be fundamental tools in determining patients suitable for implantation of an intracochlear electrode array.

Cochlea↗
PubMed1988

Uni-lateral hearing-loss with acoustic neuroma patients: electrocochleographic findings.

38 patients with proven acoustic neuroma were examined. Intratympanic electrocochleography was performed with alternating clicks of 90 dB (nHL) intensity and a stimulus rate of 20 per second; 500 sweeps were averaged. Widening of the Cochlear Action Potential (CAP)-complex by a mean of 1.6 ms was the most striking finding. Summating potentials (ratio of SP-amplitude to CAP-amplitude) were enlarged to 0.6, compared to 0.2 in healthy persons and 0.8 in patients suffering from Meniere's disease. The most noticeable result was the loss of amplitude using very short interstimulus intervals. With a stimulus-rate of 97 per second amplitudes of acoustic neuroma patients were reduced by 49.9%. Acoustic neuroma patients show pathological inner ear potentials. Some of the changes such as increased SP are found in patients with Meniere's disease, supposingly caused by endolymphatic hydrops. For tumours of the acoustic nerve the hydrops theory does not seem likely; the loss of amplitude due to adaptation within the first neuron seems to point to mechanical reasons due to the pressure of the tumour itself.

Audiometry, Evoked Response↗
PubMed1988

Chemical-analytical characterization of dihydroambazone.

Important properties of p-(thiosemicarbazido)diamino-methylen-hydrazino benzene (1; dihydroambazone) are described. The transformation of this compound into 1,4-benzoquinone guanylhydrazone thiosemicarbazone (2; ambazone) dependent on different aqueous buffer systems was investigated. The spectroscopic behaviour of the transformation product allows us to determine the content of the compound in aqueous solutions, whereas the determination in serum is much more difficult. Furthermore, TLC experiments and oxidation methods are described.

Chemical Phenomena↗
PubMed1988

[Multicenter skin tumor of the interdigitating dendritic cell].

This report concerns a multicentric skin tumor of dendritic cells. Skin-colored to reddish-brown papules and nodules erupted on the right arm of a 68-year-old man and, during the following years, spread to the upper extremities, shoulders, legs and face. Immunohistochemically the large, histiocyte-like tumor cells are Leu-6 (CD1), Leu-3a (CD4), HLA-DR/DQ and S-100 protein positive, but on thorough ultrastructural investigation were found to lack Birbeck granules. Thus, this disease represents a skin tumor of the interdigitating dendritic cell, an accessory cell which, in this case, was associated with a high content of T-lymphocytes within the cutaneous cellular infiltrate. The clinical course is characterized by periodic progression with intermittent, spontaneous regression. During a 7-year follow-up it was not possible to ascertain involvement of either lymph nodes or internal organs.

Aged↗
PubMed1988

[Increased summation potentials in patients with Menière's disease].

There have been many publications about enlarged summation potentials with Meniere patients. The phenomenon was interpreted as being due to endolymphatic hydrops. 50 patients were examined electrocochleographically who were suffering from the symptoms low-frequency hearing loss, vertigo, tinnitus and pressure in the ear. As in other previous studies a significantly enlarged negative summating potential was found in 70% of the patients. With 10 patients electrocochleography was performed before and three hours after glycerol ingestion. In 8 patients the SP became smaller, although the subjective hearing threshold improved in only 4 cases. The study shows that enlarged SP is a common finding in Meniere patients; it underlines the diagnostic value of electrocochleography in this disease.

Audiometry, Evoked Response↗
PubMed1987

[PUVA--therapy with low UV-A dose].

A long-term study on 98 psoriatic patients with an average observation time of seven years proved that PUVA therapy with low doses of UV-A is sufficient to induce complete remission of psoriasis vulgaris (chronic stationary type). After a maintenance therapy of about 7.3 irradiations over 6.5 weeks, the patients were without symptoms for 64 weeks on an average. With regard to patients showing skin type II, III, or IV, we give detailed information on the increase of UV-A doses during the first eleven days of treatment.

Adult↗