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Biomedical subjects

G Harauz

Publications and source records attributed to G Harauz.

62 records · Page 4Linked to original sources
PubMed1981

Discrepancies between radionuclide and computed tomographic scans in detecting secondary neoplastic involvement of the brain.

A radionuclide (RN) brain scan and a computed tomographic (CT) brain scan were performed on the same patient within one month on 207 occasions between February 1978 and October 1979 in order to investigate secondary neoplastic involvement of either metastatic or lymphomatous nature. The two scans were read independently of each other. There was a significant difference between the results of the two techniques in 26 of the 207 cases (13%). In 15 cases, the RN brain scan found clinically suspected secondary neoplastic involvement that was not detected by CT. In the other 11 cases, lesions detected by CT were not detected with the RN scan. Discrepancies were more frequent in patients with lymphoma than in patients with carcinoma.

Adult↗
PubMed1979

Comparison of the liver's respiratory motion in the supine and upright positions: concise communication.

The effect of the upright position, compared with the supine position, in reducing respiratory motion during liver scintigraphy has been measured in a group of 51 randomly selected patients. Little improvement in spatial resolution can be expected from simply standing the patient upright, and analog motion correction is recommended as much more effective in minimizing respiratory motion artifacts in liver scintigraphy.

Humans↗
PubMedDate not supplied

A new generation of the IMAGIC image processing system.

One of the aims of modern microscopy is to quantify two-, three-, or even four-dimensional phenomena in biology, medicine, and material sciences. The requirements imposed on software by such data processing are exemplified by the design considerations of the IMAGIC-5 software system. This system includes facilities for multivariate statistical analysis of large data sets, for correlation averaging of two-dimensional crystals, and for three-dimensional reconstruction of macromolecular structures. The molecules may be arranged as two-dimensional crystals, as helices, or as single particles with arbitrary pointgroup symmetry. IMAGIC's novel angular reconstitution approach allows for the rapid determination of three-dimensional structures of uncrystallized molecules to high resolution. The general organization, user interaction strategy, file structure, and extendibility of IMAGIC are discussed and illustrated with some practical examples.

Animals↗
PubMedDate not supplied

Structural studies on the 2.25-MDa homomultimeric phosphoenolpyruvate synthase from Staphylothermus marinus.

The phosphoenolpyruvate synthase of the hyperthermophilic archaeon Staphylothermus marinus forms an unusually large homomultimeric complex of 93 kDa subunits. Electron image analysis of negatively stained and low-dose unstained preparations showed that the complex has a single, stable characteristic view and a well-preserved core with threefold rotational symmetry. The periphery of the assembly is composed of a nebulous, possibly flexible, component. Mass measurements by scanning transmission electron microscopy yielded a molecular weight of 2250 +/- 230 kDa, confirming the well-defined nature of the structure and indicating that it is composed of 24 +/- 2.5 subunits. The stability and symmetry of the characteristic projection views suggest a polyhedral three-dimensional architecture. The novel quaternary arrangement of this enzyme might be a consequence of its adaptation to an extreme environment.

Archaea↗