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Biomedical subjects

G H Nelson

Publications and source records attributed to G H Nelson.

At least 91 records · Page 5Linked to original sources

Evaluation of a new system ("Corvac") for separating serum from blood for routine laboratory procedures.

We evaluated the suitability of a new system ("Corvac," Corning) for rapid, complete separation of cell-free serum from whole blood. Twenty-one different clinical chemical procedures were performed on about 1150 paired blood samples, several by more than one method, to afford a more comprehensive evaluation. The tube of clotted blood collected in the conventional manner ("Vacutainer") underwent a double centrifugation and served as the control sample, while its paired specimen collected in the new system was processed by a single centrifugation. We evaluated significant differences between the means of the paired samples, the standard deviations of the differences between the means, and the bias of the means for the values of each constituent for each collection method. For several tests we observed differences that were statistically but not clinically significant. Only in the case of lactate dehydrogenase were large differences consistently demonstrated.

Alkaline Phosphatase↗

Risk of respiratory distress syndrome as determined by amniotic fluid lecithin concentration.

Lecithin concentration has been determined in 476 samples of amniotic fluid collected within 72 hours of delivery. If delivery is associated with a level of lecithin of 0.100 mg/100 ml. of lecithin phosphorus or greater, the risk of RDS in the neonate is minimal, if any. If delivery is associated with a level of lecithin less than 0.100 mg/100 ml. of lecithin phosphorus, a definite risk of RDS is present. This "risk factor" is a function of the lecithin concentraion and may be expressed in terms of a simple mathematical equation. The equation, log y equals minus 1.0187 minus 0.0101 chi, expresses the relationship in a highly significant manner (r equals 0.99) where y equals lecithin concentration and chi equals risk of RDS. In managing individual high-risk patients, our general policy is to weigh the chemically determined "risk factor" of RDS if delivery is done against the clinically determined "risk factors" involved if delivery is delayed. By comparing the various risks involved, appropriate management is decided upon.

Amniocentesis↗

Effects on turkey poults of rations containing corn invaded by Fusarium tricinctum (Cda.) Sny. & Hans.

Consumption of an otherwise balanced ration containing 1% of corn invaded by Fusarium tricinctum isolate 2061-C resulted in the death of 13% of turkey poults within 35 days, in decreased feed efficiency and weight gain, and moderate development of bilateral necrotic lesions at angles of the mouth, especially in those that succumbed. Consumption of a ration with 2% of corn invaded by F. tricinctum resulted in death of 60 to 83% of the birds, in greatly reduced growth and feed efficiency in the survivors, and in development of severe mouth lesions. Consumption of rations containing 5, 10, and 20% of corn invaded by the fungus resulted in death of all birds in 5 to 15 days.

Animal Feed↗

Effect on young swine of consumption of rations containing corn invaded by Fusarium roseum.

Both male and female pigs given a ration containing corn invaded by Fusarium roseum, in amounts sufficient to provide 500 to 600 ppm of F-2, for the first 64 days of the test and which for another 60 days were given a commercial pig ration were much lower in weight than the controls which were given a commercial pig ration throughout. In relation to the weight of the animals, in the pigs receiving the ration containing F-2, the weight of the uterine horn of the gilts was much greater and the weight of the testes of the males was much less than the weight of the same organs of the controls.

Animal Feed↗