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Biomedical subjects

G H Miller

Publications and source records attributed to G H Miller.

At least 127 records · Page 7Linked to original sources

A brief scale for predicting rehospitalization of former psychiatric patients.

Community adjustment of former psychiatric patients has been found to relate highly to the likelihood of rehospitalization and community tenure. The present study examined the ability of a community adjustment scale and various other patient characteristics to predict rehospitalization. Multiple regression analysis using rehospitalization as the dependent variable identified thirteen items including twelve from the community adjustment scale, which combined to provide a highly accurate prediction. The brief scale (13 items) which is now being cross-validated is potentially a useful tool for clinical evaluation and planning of follow-up series to former patients.

Female↗

Post-prostatectomy impotence.

With the help of the principles of rapid eye movement sleep and nocturnal penile tumescence, 14 patients who underwent transurethral prostatectomy were studied by monitoring the electroencephalograph, electro-oculograph and penile plethysmograph activity preoperatively and postoperatively. No instance of complete loss of penile erection was found postoperatively. The need for objective rather than subjective data is emphasized.

Aged↗

Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic.

Netilmicin (Sch 20569) is a new broad-spectrum semisynthetic aminoglycoside derived from sisomicin. Netilmicin was compared to gentamicin, tobramycin, and amikacin in a variety of in vitro test systems as well as in mouse protection tests. Netilmicin was found to be similar in activity to gentamicin against aminoglycoside-susceptible strains in both in vitro and in vivo tests. Netilmicin was also active against many aminoglycoside-resistant strains of gram-negative bacteria, particularly those known to possess adenylating enzymes (ANT 2') or those with a similar resistance pattern. Netilmicin was found to be markedly less toxic than gentamicin in chronic studies in cats, although gentamicin appeared less toxic in acute toxicity tests in mice. The concentrations of netilmicin and gentamicin in serum were compared in dogs after intramuscular dosing, and the pharmacokinetics including peak concentrations in serum were found to be similar.

Amikacin↗