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Biomedical subjects

G H Li

Publications and source records attributed to G H Li.

68 records · Page 4Linked to original sources

[Smoking and mortality in lung cancer].

From 1978 to 1980, a retrospective epidemiologic survey on mortality of lung cancer was undertaken in Taiyuan, an industrial city of Shanxi Province. The average crude mortality was 14.35/100,000, the third place in death of the malignancies. In the male the mortality was 20.46 ranking the second. In the female, it was 7.26, the fourth. It was increased markedly in the man over 35 years old and in the woman over 40. The death rate was higher in the urban districts than in the suburbs of the city. This difference was statistically significant (P less than 0.05). In the urban districts, suburbs of this city and its countryside, both the incidence and mortality showed significant differences in smoking and non-smoking groups (P less than 0.01). This result indicates that smoking is related to lung cancer. The mortality of malignant tumors was 176.69/100,000 in the smoking group, whereas in the non-smoking group, it remained at the level of 46.65/100,000. It should be further studied that how smoking exerts influence on the other malignancies. The relative risks (RR) of lung cancer to smoking were 3.07 in the male and 2.60 in the female with a total RR of 3.52. The data mentioned above suggest that cigarette smoking plays an important role in the cause of lung cancer. Hence, to advocate abstinence of smoking is of vital importance, especially in the industrial districts.

Adolescent↗

[Surgical management of soft tissue sarcoma].

From 1964 to 1978, 313 patients with soft tissue sarcoma were treated in our hospital by resection and followed over 5 years. 192 patients were males and 121 were females. The sex ratio was 1.5:1. In the 190 cases who developed postoperative recurrence, 55 were in the head and neck, 136 in the trunk and 122 in the limbs and 23 (7.4%) as metastasis in the lymph nodes. By pathology, the common types were fibrosarcoma (86 cases), neurofibrosarcoma (66 cases) and rhabdomyosarcoma (32 cases). All the 313 patients were treated by resection, the overall 5 and 10 year survival rates were 47.6% and 35.8%. The 5 year survival rate was 47.9% in the 117 patients treated by local resection, 62.7% in the 75 by extensive resection, 18.6% in the 43 by amputation and 48.7% in the 78 by combination of resection and irradiation. According to the UICC TNM staging system, the 5 year survival was 60% in stage I, 46.9% in stage II, 40% in stage III and 22.2% in stage IV. In this series, discussion of the treatment modalities and prognosis factors in emphasized.

Adolescent↗

[Ligation of hepatic artery combined with radiotherapy in the treatment of unresectable primary liver carcinoma].

The ligation of hepatic artery combined with radiotherapy is effective in the treatment of unresectable liver carcinoma. Our data show that some of the lesions, upon ligation of hepatic artery, underwent shrinkage and became darkened in color, were designated as "hypervascular type". The others which did not give these responses were designated as "oligovascular type". Yet both belonged to the hepatocellular carcinoma pathologically. In this series the total response rate was 71.4% (10/14). There were 3 patients who had complete regression. The 6-month survival rate was 85.7% (12/14), the one-year, 57.1% (8/14), and the 2-year, 21.4% (3/14). The median survival interval was 14 months (ranging from 2-36 months). The "mass type" which was localized and "hypervascular" responded well to treatment. The application of radiotherapy according to the location and the size of the tumor after the ligation of hepatic artery may be able to improve the result and reduce the side effects of irradiation.

Adult↗