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Biomedical subjects

G H Irvine

Publications and source records attributed to G H Irvine.

At least 19 recordsLinked to original sources

Adenoid cystic carcinoma of the sublingual salivary gland in a 16-year-old female--report of a case and review of the literature.

Tumours of the sublingual salivary gland are exceptionally rare. The present case report describes an adenoid cystic carcinoma of the sublingual salivary gland occurring in a 16-year-old girl, in itself an uncommon event. In addition, an interesting feature of the presentation was obstruction of the ipsilateral submandibular gland due to involvement of Wharton's duct.

Adolescent↗

Oral squamous cell carcinoma after allogeneic bone marrow transplantation for Fanconi anaemia.

We report a case of oral squamous cell carcinoma (SCC) originating in the buccal mucosa of an 18-year-old female patient with chronic graft-versus-host disease (GVHD) 9 years after HLA-identical sibling bone marrow transplantation (BMT) for Fanconi anaemia (FA). The case highlights the problems of malignant change in FA and also the increased risk of second malignancy after BMT. The literature is reviewed with regard to previous cases and the possible aetiology of tumour formation. A high index of suspicion to any epithelial lesion in FA is appropriate so that early diagnosis may lead to improved prognosis.

Adolescent↗

Avoiding artefacts in oral biopsies: the punch biopsy versus the incisional biopsy.

Fifty oral biopsy specimens were removed, 24 with a punch and 26 by conventional incision with a scalpel. All specimens were routinely processed in the histopathology laboratory and examined for artefacts. Significantly fewer artefacts were found in the punch biopsy group compared to the incisional biopsy group. Access for the punch was not found to be a problem.

Artifacts↗

Fronto-sternal traction: an adjunct to orthognathic surgery.

A case is reported in which an unexpected occlusal result arose following bimaxillary osteotomy for correction of a skeletal Class III discrepancy. In order to correct the occlusion, the mandible was protracted independently of the recently plated maxilla, by means of a fronto-sternal traction device.

Adult↗

Visceral leishmaniasis: an unusual cervical presentation.

Visceral leishmaniasis is an infectious disease with a classical clinical presentation of fever, anaemia and splenomegaly forming the three cardinal signs. A rare presentation of the disease is described where cervical lymph node enlargement was the only sign and there were no symptoms. It is emphasised that with extensive travel to and from areas of endemic leishmaniasis now established, it is important that clinicians and pathologists become acquainted with the characteristics of the disease.

Animals↗

Ossifying fibromyxoid tumour of soft parts--a new tumour of the parotid/zygomatic arch region.

The ossifying fibromyxoid tumour of soft parts was first described as recently as 1989 by Enzinger has not been previously reported in the maxillofacial literature. This tumour has a proven record of recurrence and a potential in a few cases to become malignant and to metastasise. Being such a rare and relatively newly described tumour it has proved to be difficult to diagnose and manage. In order to illustrate these difficulties we describe a case in which such a tumour occurred in the parotid/zygomatic arch region and recurred three times following surgical removal over a period of 24 years. Since the tumour has a pseudo-capsule containing nests of tumour cells, we recommend that it could be removed from the head and neck region with a wide margin of excision.

Adult↗

Fine needle aspiration cytology in maxillofacial surgery--experience in a district general hospital.

101 fine needle aspirations of 82 head and neck masses in 72 patients performed in one maxillofacial unit over a 5-year period were studied retrospectively. Satisfactory reports were obtained for 69 masses. Fifty six (81.2%) were confirmed histologically and 13 (18.8%) by clinical follow up of at least 6 months' duration. The sensitivity was 96.7% and specificity 100% with a positive predictive value of 100%. No complications were recorded. Provided the unsatisfactory specimens are correctly recognised this technique provides a useful aid in the management of head and neck masses.

Adenoma, Pleomorphic↗

Audit of antibiotic policy and wound infection in neck surgery.

Neck surgery on 100 consecutive patients in a unit with an established antibiotic policy was studied. An infection rate of 3% was recorded, comparing well with previously published studies. There were no major sequelae in the infected cases. A policy of no perioperative antibiotics for 'clean' surgery for benign disease, cefuroxime for 'clean' surgery for malignant disease and cefuroxime plus metronidazole for 'clean contaminated' surgery is vindicated.

Anti-Bacterial Agents↗

Intra-oral carcinoma simulating benign oral disease.

Intra-oral carcinoma can present in a variety of ways. Whilst carcinoma classically presents as an irregular, indurated, painless mass or ulcer, it is also recognised as being a great 'mimic' of benign lesions. A series of four cases of intra-oral squamous cell carcinoma is presented in which the initial presentation suggested a lesion of benign or dental origin. Factors which raise the index of suspicion are discussed.

Aged↗

A simple method for fixation of mandibular fractures.

A useful but underused technique of mandibular fixation is described. Its main advantages over more traditional techniques are that it is easily and rapidly applied, suitable for both children and adults, and generally well tolerated. The method can be employed where only a few teeth are present and in displaced fractures together with an intraosseous buccal plate wire. It is a method that can be recommended for use in nonmaxillofacial units and in areas where only basic equipment and facilities are available.

Bone Wires↗